Irbesartan

Generic Name
Irbesartan
Brand Names
Avalide, Avapro, Ifirmacombi, Karvea, Karvezide, Irbesartan Teva, Ifirmasta (previously Irbesartan Krka), Irbesartan Zentiva (previously Irbesartan Winthrop), Aprovel
Drug Type
Small Molecule
Chemical Formula
C25H28N6O
CAS Number
138402-11-6
Unique Ingredient Identifier
J0E2756Z7N
Background

Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy. It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated with a dry co...

Indication

Irbesartan is indicated to treat hypertension and diabetic nephropathy in hypertensive patients with type 2 diabetes, elevated serum creatinine, and proteinuria. A combination product with hydrochlorothiazide is indicated for hypertension in patients with uncontrolled hypertension with monotherapy or first line in patients not expected to be well controlled ...

Associated Conditions
Diabetic Nephropathy, Hypertension
Associated Therapies
-
Clinical Trials
Related News

Irbesartan in the Treatment of Hypertensive Patients With Metabolic Syndrome

First Posted Date
2005-05-10
Last Posted Date
2011-04-15
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
400
Registration Number
NCT00110422
Locations
🇪🇸

Local Institution, Zaragoza, Spain

Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney

First Posted Date
2005-03-28
Last Posted Date
2005-06-24
Lead Sponsor
Melbourne Health
Target Recruit Count
60
Registration Number
NCT00106561
Locations
🇦🇺

Department of Nephrology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia

Irbesartan in Heart Failure With Preserved Systolic Function (I-Preserve)

Phase 3
Completed
Conditions
Congestive Heart Failure
Interventions
Drug: Placebo
Drug: Irbesartan
First Posted Date
2004-11-02
Last Posted Date
2015-04-07
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
4128
Registration Number
NCT00095238
Locations
🇬🇧

Local Institution, Londonderry, United Kingdom

Prevention of Kidney Transplant Rejection

First Posted Date
2001-08-31
Last Posted Date
2013-01-25
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Registration Number
NCT00005010
Locations
🇺🇸

Ilene Blechman-Krom, Rockville, Maryland, United States

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