Desmopressin
生产企业：Sanofi aventis us llc, Bedford laboratories div ben venue laboratories inc，另有 9 家
Desmopressin is a synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia.
Desmopressin is a synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia.
Upon binding of desmopressin to V2 receptors in the basolateral membrane of the cells of the distal tubule and collecting ducts of the nephron, adenylyl cyclase is stimulated. The resulting intracellular cascades in the collecting duct lead to increased rate of insertion of water channels, called aquaporins, into the lumenal membrane and enhanced the permeability of the membrane to water .
1.治疗中枢性尿崩症，可减少尿量、提高尿渗透压、降低血浆渗透压； 2.用于尿崩症的诊断和鉴别诊断； 3.用于治疗夜间遗尿症（六岁或以上的患者）； 4.部分类型（甲型血友病和Ⅰ型血管性假血友病）的血友病及其他出血性疾病。
共 7 项相关疾病
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
