Desmopressin

Generic Name
Desmopressin
Brand Names
Ddavp, Nocdurna, Octostim
Drug Type
Small Molecule
Chemical Formula
C46H64N14O12S2
CAS Number
16679-58-6
Unique Ingredient Identifier
ENR1LLB0FP
Background

Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the stimulation of increased plasm...

Indication

1.治疗中枢性尿崩症，可减少尿量、提高尿渗透压、降低血浆渗透压；

2.用于尿崩症的诊断和鉴别诊断；

3.用于治疗夜间遗尿症（六岁或以上的患者）；

4.部分类型（甲型血友病和Ⅰ型血管性假血友病）的血友病及其他出血性疾病。

Associated Conditions
Bleeding, Hypothalamic Injury-induced Obesity (HIO), Nocturia, Nocturnal Polyuria, Polydipsia, Polyuria, Primary Nocturnal Enuresis
Associated Therapies
-
Clinical Trials
Related News

Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome

Phase 2
Recruiting
Conditions
Cushing Syndrome
Interventions
Drug: Desmopressin
Drug: Dexamethasone
First Posted Date
2024-10-10
Last Posted Date
2024-12-19
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
140
Registration Number
NCT06635629
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Desmopressin Monotherapy for Monosymptomatic Nocturnal Enuresis

Not Applicable
Recruiting
Conditions
Nocturnal Enuresis
Interventions
Drug: Desmopressin
First Posted Date
2024-02-29
Last Posted Date
2024-04-23
Lead Sponsor
Al-Azhar University
Target Recruit Count
50
Registration Number
NCT06285006
Locations
🇪🇬

Alazhar university, Assiut, Egypt

Analysis of the Clinical Efficacy of Intravenous Application of Hemostatic Drugs in Improving the Clarity of Vision Under Endoscope, Perioperative Bleeding Volume and Anti-inflammatory Effect of Spinal Endoscopic Lumbar Fusion

First Posted Date
2024-02-13
Last Posted Date
2024-03-15
Lead Sponsor
Chengdu University of Traditional Chinese Medicine
Target Recruit Count
126
Registration Number
NCT06255366

Selective Serotonin Reuptake Inhibitors, Fluoxetine Versus the Standard Oral Desmopressin for Management of Mono-symptomatic Nocturnal Enuresis.

Not Applicable
Active, not recruiting
Conditions
Nocturnal Enuresis
Enuresis
Enuresis, Nocturnal
Interventions
Drug: Fluoxetine 20 MG
Drug: Desmopressin
First Posted Date
2023-12-29
Last Posted Date
2023-12-29
Lead Sponsor
Fayoum University Hospital
Target Recruit Count
60
Registration Number
NCT06185361
Locations
🇪🇬

Faculty of medicine, Fayoum University, Fayoum, Egypt

Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia

Phase 3
Not yet recruiting
Conditions
Hyponatremia
Interventions
Drug: Standard hyponatremia treatment
Drug: DDAVP
First Posted Date
2023-08-31
Last Posted Date
2024-06-24
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
260
Registration Number
NCT06020495
Locations
🇫🇷

Médecine Intensive et Réanimation - Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France

🇫🇷

Médecine Intensive et Réanimation - Hôpital Avicenne, Bobigny, France

🇫🇷

Médecine Intensive et Réanimation - Hôpital Louis Mourier, Colombes, France

and more 10 locations

Genetic Factors of the Desmopressin Response in Carriers of Hemophilia A

First Posted Date
2023-08-31
Last Posted Date
2023-08-31
Lead Sponsor
Groupe Maladies hémorragiques de Bretagne
Target Recruit Count
361
Registration Number
NCT06020456
Locations
🇫🇷

University hospital of Bordeaux, Bordeaux, France

🇫🇷

University hospital of Brest, Brest, France

🇫🇷

University hospital of Lille, Lille, France

and more 9 locations

Adding Desmopressin to Tamsulosin for Treatment of BPH

First Posted Date
2023-07-14
Last Posted Date
2023-07-14
Lead Sponsor
Mansoura University
Target Recruit Count
160
Registration Number
NCT05945420
Locations
🇪🇬

Urology and nephrology center, Mansoura, Outside U.S./Canada, Egypt

Genetic Influence of Genetic Factors Influencing the Desmopressin's Efficacy in Mild/Moderate Hemophilia A

First Posted Date
2022-11-28
Last Posted Date
2022-11-28
Lead Sponsor
Groupe Maladies hémorragiques de Bretagne
Target Recruit Count
800
Registration Number
NCT05628558
Locations
🇫🇷

University hospital of Rennes, Rennes, Bretagne, France

Safety Outcomes Post Kidney Biopsy - Randomized Clinical Evaluation of Efficacy of Desmopressin

First Posted Date
2022-07-20
Last Posted Date
2022-11-25
Lead Sponsor
Medical University of Bialystok
Target Recruit Count
424
Registration Number
NCT05467033
Locations
🇵🇱

II Department of Nephrology and Hypertension, Bialystok, Poland

Posterior Tibial Nerve Stimulation Vs Desmopressin In Children With Primary Monosymptomatic Nocturnal Enuresis

First Posted Date
2020-09-11
Last Posted Date
2020-09-11
Lead Sponsor
Cairo University
Target Recruit Count
80
Registration Number
NCT04545931
Locations
🇪🇬

Abo ElRish children hospital, Cairo, Egypt

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