Progesterone

Generic Name
Progesterone
Brand Names
Bijuva, Crinone, Endometrin, Prochieve, Prometrium
Drug Type
Small Molecule
Chemical Formula
C21H30O2
CAS Number
57-83-0
Unique Ingredient Identifier
4G7DS2Q64Y
Background

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prev...

Indication

Gelatinized capsules

The gelatinized capsules are indicated for use in the prevention of endometrial hyperplasia in non-hysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also indicated for use in secondary amenorrhea .

Vaginal gel
...

Associated Conditions
Abnormal Uterine Bleeding, Amenorrhea, Endometrial hyperplasia caused by conjugated estrogen, Moderate to Severe Vasomotor Symptoms, Pregnancy, Secondary Amenorrhea, Recurrent spontaneous preterm birth
Associated Therapies
Assisted Reproductive Technology therapy

Vaginal Progesterone in the Treatment of Cervical Dysplasia Grade I and II

Phase 2
Completed
Conditions
First Posted Date
2005-11-01
Last Posted Date
2012-03-09
Lead Sponsor
Medical University of Vienna
Target Recruit Count
40
Registration Number
NCT00247169
Locations
🇦🇹

Dept OB/GYN, Med University of Vienna, Vienna, Austria

Progesterone for the Treatment of Cocaine Dependence - 1

First Posted Date
2005-09-22
Last Posted Date
2020-10-08
Lead Sponsor
University of Minnesota
Target Recruit Count
96
Registration Number
NCT00218257
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

Anti-Estrogens - A Potential Treatment for Bipolar Affective Disorder in Women?

First Posted Date
2005-09-21
Last Posted Date
2008-10-24
Lead Sponsor
The Alfred
Target Recruit Count
51
Registration Number
NCT00206544
Locations
🇦🇺

Bayside Health - The Alfred Hospital, Melbourne, Victoria, Australia

Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease

Phase 2
Completed
Conditions
First Posted Date
2000-08-21
Last Posted Date
2009-01-15
Lead Sponsor
National Center for Research Resources (NCRR)
Target Recruit Count
45
Registration Number
NCT00006399
Locations
🇺🇸

Clinical Neuroscience Research Unit, University of Vermont, Burlington, Vermont, United States

Effects of Hormone Replacement Therapy on Inflammation and Stiffening of Artery Walls

Phase 2
Completed
Conditions
First Posted Date
2000-04-12
Last Posted Date
2008-03-04
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Target Recruit Count
25
Registration Number
NCT00005108
Locations
🇺🇸

National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, United States

A Treatment Study for Premenstrual Syndrome (PMS)

First Posted Date
1999-11-04
Last Posted Date
2023-03-02
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
60
Registration Number
NCT00001259
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

The Effects of Reproductive Hormones on Mood and Behavior

First Posted Date
1999-11-04
Last Posted Date
2022-03-22
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
100
Registration Number
NCT00001322
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

The Role of Hormones in Postpartum Mood Disorders

First Posted Date
1999-11-04
Last Posted Date
2024-12-19
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
100
Registration Number
NCT00001481
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Postmenopausal Hormone Therapy in Unstable Angina

First Posted Date
1999-10-28
Last Posted Date
2016-02-18
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000601
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