MedPath

Oxygen

Generic Name
Oxygen
Brand Names
Alnox, Ez-OX, Heliox, Oxygen, Southern Medical
Drug Type
Small Molecule
Chemical Formula
O2
CAS Number
7782-44-7
Unique Ingredient Identifier
S88TT14065
Background

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.

Indication

Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia to reduce the extent of hypoxia-induced tissue damage and malfunction.

Associated Conditions
Anemia, Cancer, Hypoxemia, Hypoxia, Migraine, Polycythemia, Pulmonary Hypertension (PH), Respiratory Disorders, Sleep Apnea
Associated Therapies
-

Effect of Heliox on RSV Bronchiolitis

Phase 3
Completed
Conditions
RSV Infection
Acute Bronchiolitis
Interventions
First Posted Date
2017-05-31
Last Posted Date
2017-05-31
Lead Sponsor
Wael Seliem
Target Recruit Count
104
Registration Number
NCT03171142

Adjunctive Nitrous Oxide During ED Incision and Drainage of Abscess

Not Applicable
Terminated
Conditions
Abscess
Interventions
First Posted Date
2017-04-25
Last Posted Date
2021-04-27
Lead Sponsor
Albert Einstein Healthcare Network
Target Recruit Count
41
Registration Number
NCT03127371
Locations
🇺🇸

Einstein Medical Center Philadelphia, Philadelphia, Pennsylvania, United States

High-Flow-Therapy for the Treatment of Cheyne-Stokes-Respiration in Chronic Heart Failure

Phase 3
Terminated
Conditions
Heart Failure,Congestive
Interventions
Other: Placebo
Drug: Oxygen
First Posted Date
2017-04-06
Last Posted Date
2018-09-26
Lead Sponsor
Heart and Diabetes Center North-Rhine Westfalia
Target Recruit Count
14
Registration Number
NCT03102827
Locations
🇩🇪

Heart and Diabetes Center North-Rhine-Westphalia, Bad Oeynhausen, Germany

Long-term Oxygen Therapy in Patients With Chronic Obstructive Pulmonary Disease Who Live at High Altitude

Not Applicable
Active, not recruiting
Conditions
COPD
Interventions
First Posted Date
2017-01-13
Last Posted Date
2024-03-28
Lead Sponsor
Fundación Neumologica Colombiana
Target Recruit Count
220
Registration Number
NCT03020212
Locations
🇨🇴

Fundación Neumológica Colombiana, Bogotá, Colombia

High Flow Nasal Cannula vs Low Flow Oxygen Therapy in Bronchiolitis

Phase 4
Terminated
Conditions
Bronchiolitis
Interventions
First Posted Date
2017-01-09
Last Posted Date
2020-09-04
Lead Sponsor
IRCCS Burlo Garofolo
Target Recruit Count
30
Registration Number
NCT03015051
Locations
🇮🇹

Ospedale A. Cardarelli, Campobasso, Molise, Italy

🇮🇹

Ospedale Maggiore, Bologna, Emilia Romagna, Italy

🇮🇹

Ospedale Morgagni-Pierantoni, Forlì, Emilia Romagna, Italy

and more 12 locations

Use of Oxygen in Heart Failure With Preserved Ejection Fraction

Phase 2
Completed
Conditions
Heart Failure
Interventions
First Posted Date
2016-10-31
Last Posted Date
2019-06-26
Lead Sponsor
Hull University Teaching Hospitals NHS Trust
Target Recruit Count
50
Registration Number
NCT02949531

Influence of Oxygen Target Range on Intermittent Hypoxemia in Preterm Infants

Not Applicable
Conditions
Intermittent Hypoxemia
Apnea of Prematurity
Interventions
First Posted Date
2016-04-19
Last Posted Date
2016-04-19
Lead Sponsor
University of Ulm
Target Recruit Count
36
Registration Number
NCT02743988
Locations
🇩🇪

University Medical Center, Ulm University, Ulm, Baden-Württemberg, Germany

Effect of Peri-operative Supplemental Oxygen in Wound Infection After Appendectomy

Not Applicable
Completed
Conditions
Wound Infection
Perioperative Hyperoxygenation
Interventions
First Posted Date
2016-02-22
Last Posted Date
2016-05-06
Lead Sponsor
Lady Hardinge Medical College
Target Recruit Count
60
Registration Number
NCT02687217

Effect of Ambulatory Oxygen on the Walking Test in Patients With Pulmonary Fibrosis

Phase 2
Completed
Conditions
Pulmonary Fibrosis
Interventions
First Posted Date
2016-01-29
Last Posted Date
2016-01-29
Lead Sponsor
University of Siena
Target Recruit Count
32
Registration Number
NCT02668029

The Utility of Oxygen Insufflation During Flexible Fiberoptic Bronchoscope-guided Intubation

Not Applicable
Completed
Conditions
Lumbar Spinal Stenosis
Interventions
First Posted Date
2015-12-09
Last Posted Date
2019-07-09
Lead Sponsor
Yonsei University
Target Recruit Count
36
Registration Number
NCT02625194
Locations
🇰🇷

Gangnam severance hospital, Seoul, Korea, Republic of

© Copyright 2025. All Rights Reserved by MedPath