Tramadol
- Generic Name
- Tramadol
- Brand Names
- Conzip, Durela, Qdolo, Ralivia, Ryzolt, Seglentis, Tridural, Ultracet, Ultram, Zytram
- Drug Type
- Small Molecule
- Chemical Formula
- C16H25NO2
- CAS Number
- 27203-92-5
- Unique Ingredient Identifier
- 39J1LGJ30J
- Background
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...
- Indication
Tramadol is approved for the management of moderate to severe pain in adults.
Tramadol is also used off-label in the treatment of premature ejaculation.
- Associated Conditions
- Acute Pain, Premature Ejaculation, Severe Pain, Acute, moderate, severe Pain, Moderate Pain
- Associated Therapies
- -
Minimizing Narcotic Analgesics After Endocrine Surgery
- First Posted Date
- 2018-03-19
- Last Posted Date
- 2021-05-11
- Lead Sponsor
- Minerva A Romero Arenas
- Target Recruit Count
- 126
- Registration Number
- NCT03469310
- Locations
- 🇺🇸
GME General Surgery Clinic, Edinburg, Texas, United States
Impact of Tramadol and Oxycodone on Sleep Apnea
- First Posted Date
- 2018-03-05
- Last Posted Date
- 2021-01-27
- Lead Sponsor
- Centre Hospitalier Universitaire Vaudois
- Target Recruit Count
- 60
- Registration Number
- NCT03454217
- Locations
- 🇨🇭
Lausanne University Hospital, Lausanne, Vaud, Switzerland
Evaluate Safety of Tramadol in the Management of Postoperative Pain Following Surgery
- First Posted Date
- 2018-01-10
- Last Posted Date
- 2021-03-09
- Lead Sponsor
- Avenue Therapeutics, Inc.
- Target Recruit Count
- 251
- Registration Number
- NCT03395808
- Locations
- 🇺🇸
Lotus Clinical Research, Pasadena, California, United States
Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
- Conditions
- Interventions
- First Posted Date
- 2017-12-26
- Last Posted Date
- 2017-12-26
- Lead Sponsor
- University of Malaya
- Target Recruit Count
- 191
- Registration Number
- NCT03383315
- Locations
- 🇲🇾
Sarawak General Hospital, Kuching, Sarawak, Malaysia
Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair
- First Posted Date
- 2017-12-21
- Last Posted Date
- 2021-04-08
- Lead Sponsor
- Hospital Italiano de Buenos Aires
- Target Recruit Count
- 50
- Registration Number
- NCT03380533
- Locations
- 🇦🇷
Hospital Italiano de Buenos Aires, Buenos Aires, Caba, Argentina
Treatment of Neuropathic Pain in Leprosy
- Conditions
- Interventions
- First Posted Date
- 2017-10-27
- Last Posted Date
- 2022-02-23
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 102
- Registration Number
- NCT03324035
- Locations
- 🇧🇷
Hospital Das Clínicas da Faculdade de Medicina da USP, São Paulo, SP, Brazil
Omnitram Pharmacokinetic and Analgesic Study Following CY2D6 Inhibition With Paroxetine In Healthy Volunteers
- First Posted Date
- 2017-10-18
- Last Posted Date
- 2017-12-28
- Lead Sponsor
- Syntrix Biosystems, Inc.
- Target Recruit Count
- 60
- Registration Number
- NCT03312777
- Locations
- 🇺🇸
PRA Health Sciences, Salt Lake City, Utah, United States
Effect of Tramadol in Prevention of Postpartum Depression
- Conditions
- Interventions
- First Posted Date
- 2017-10-13
- Last Posted Date
- 2019-08-14
- Lead Sponsor
- Xinqiao Hospital of Chongqing
- Target Recruit Count
- 1230
- Registration Number
- NCT03309163
- Locations
- 🇨🇳
Xinqiao Hospital, Third Military Medical University, Chongqing, Chongqing, China
Analgesic Effect of Quadratus Lumborum Block Application After Laparoscopic Cholecystectomy Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-10-13
- Last Posted Date
- 2017-12-29
- Target Recruit Count
- 60
- Registration Number
- NCT03308955
- Locations
- 🇹🇷
University of Health Sciences,,Bursa Yuksek Ihtisas Training and Research Hospital,, Bursa, Turkey
Tramadol Versus Placebo in the Management of Postoperative Pain Following Bunionectomy
- First Posted Date
- 2017-09-21
- Last Posted Date
- 2020-03-19
- Lead Sponsor
- Avenue Therapeutics, Inc.
- Target Recruit Count
- 409
- Registration Number
- NCT03290378
- Locations
- 🇺🇸
Lotus Clinical Research, Pasadena, California, United States
🇺🇸H.D. Research Corporation, Houston, Texas, United States
🇺🇸Trovare Clinical Research, Bakersfield, California, United States
Drug Development Updates
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