Lisinopril
- Generic Name
- Lisinopril
- Brand Names
- Prinivil, Qbrelis, Zestoretic, Zestril
- Drug Type
- Small Molecule
- Chemical Formula
- C21H31N3O5
- CAS Number
- 76547-98-3
- Unique Ingredient Identifier
- 7Q3P4BS2FD
- Background
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction. Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system. ACEIs are commonly used as a first line therap...
- Indication
Lisinopril is indicated for the treatment of acute myocardial infarction, hypertension in patients ≥6 years, and as an adjunct therapy for heart failure. A combination product with hydrochlorothiazide is indicated for the treatment of hypertension.
- Associated Conditions
- Acute Myocardial Infarction (AMI), Cardiovascular Events, Congestive Heart Failure (CHF), Diabetic Nephropathy, Hypertension, Migraine
- Associated Therapies
- -
Safety Study of Lisinopril in Children and Adolescents With a Kidney Transplant
- First Posted Date
- 2011-12-14
- Last Posted Date
- 2015-07-08
- Lead Sponsor
- Uptal Patel
- Target Recruit Count
- 26
- Registration Number
- NCT01491919
- Locations
- 🇺🇸
University of Alabama, Birmingham, Alabama, United States
🇺🇸University of Michigan, Ann Arbor, Michigan, United States
🇺🇸Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia, United States
The Effect and Safety of Lisinopril in Non-hypertensive Men With Infertility From Low Sperm Count
- First Posted Date
- 2011-08-04
- Last Posted Date
- 2013-11-25
- Lead Sponsor
- University Of Nigeria Teaching Hospital
- Target Recruit Count
- 33
- Registration Number
- NCT01409837
- Locations
- 🇳🇬
University of Nigeria Teaching Hospital, Ituku-Ozalla,, Enugu, Nigeria
A Pharmacodynamic/Pharmacokinetic Study of Aleglitazar in Patients With Type 2 Diabetes Mellitus on Treatment With Lisinopril
- Conditions
- Interventions
- First Posted Date
- 2011-07-20
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 55
- Registration Number
- NCT01398267
A Comparative Bioavailability Study of Lisinopril Tablets, 40 mg - Effect of Food Study
- Conditions
- Interventions
- First Posted Date
- 2011-06-27
- Last Posted Date
- 2011-06-27
- Lead Sponsor
- Par Pharmaceutical, Inc.
- Target Recruit Count
- 18
- Registration Number
- NCT01380431
- Locations
- 🇺🇸
PharmaKinetics Laboratories, Inc., Baltimore, Maryland, United States
Comparative Bioavailability Study of Lisinopril Tablets, 10 mg
- First Posted Date
- 2011-06-17
- Last Posted Date
- 2011-06-17
- Lead Sponsor
- Par Pharmaceutical, Inc.
- Target Recruit Count
- 36
- Registration Number
- NCT01375244
- Locations
- 🇺🇸
PharmaKinetics Laboratories, Inc., Baltimore, Maryland, United States
A Study of the Effect of LY2189265 on Two Blood Pressure Drugs
- Conditions
- Interventions
- First Posted Date
- 2011-03-29
- Last Posted Date
- 2014-10-08
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 51
- Registration Number
- NCT01324388
- Locations
- 🇺🇸
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Dallas, Texas, United States
Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril
- Conditions
- Interventions
- First Posted Date
- 2010-12-13
- Last Posted Date
- 2015-05-20
- Lead Sponsor
- Scripps Translational Science Institute
- Target Recruit Count
- 2
- Registration Number
- NCT01258764
- Locations
- 🇺🇸
Scripps Clinic, La Jolla, California, United States
Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors
- First Posted Date
- 2010-11-04
- Last Posted Date
- 2018-08-28
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 6
- Registration Number
- NCT01234922
- Locations
- 🇺🇸
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Effect of Angiotensin Converting Enzyme Inhibitor, Lisinopril, on Renal Blood Flow and Its Correlation With Proteinuria Reduction in Subjects With Type 2 Diabetes and Kidney Disease
- First Posted Date
- 2010-04-09
- Last Posted Date
- 2017-05-12
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 6
- Registration Number
- NCT01101269
- Locations
- 🇺🇸
University of Virginia Health System, Charlottesville, Virginia, United States
Blood Pressure Effects of Nebivolol Versus Lisinopril in New Onset or Worsening Hypertension Induced by Bevacizumab
- First Posted Date
- 2010-02-25
- Last Posted Date
- 2012-04-06
- Lead Sponsor
- University of Mississippi Medical Center
- Registration Number
- NCT01076140
- Locations
- 🇺🇸
University of Mississippi Medical Center, Jackson, Mississippi, United States
Drug Development Updates
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