Lisinopril
- Generic Name
- Lisinopril
- Brand Names
- Prinivil, Qbrelis, Zestoretic, Zestril
- Drug Type
- Small Molecule
- Chemical Formula
- C21H31N3O5
- CAS Number
- 76547-98-3
- Unique Ingredient Identifier
- 7Q3P4BS2FD
- Background
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction. Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system. ACEIs are commonly used as a first line therap...
- Indication
Lisinopril is indicated for the treatment of acute myocardial infarction, hypertension in patients ≥6 years, and as an adjunct therapy for heart failure. A combination product with hydrochlorothiazide is indicated for the treatment of hypertension.
- Associated Conditions
- Acute Myocardial Infarction (AMI), Cardiovascular Events, Congestive Heart Failure (CHF), Diabetic Nephropathy, Hypertension, Migraine
- Associated Therapies
- -
Paramedic Initiated Lisinopril For Acute Stroke Treatment
- First Posted Date
- 2010-02-10
- Last Posted Date
- 2017-03-30
- Lead Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
- Target Recruit Count
- 14
- Registration Number
- NCT01066572
- Locations
- 🇬🇧
Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, Tyne and Wear, United Kingdom
🇬🇧North East Ambulance Service NHS Trust, Newcastle upon Tyne, Tyne and Wear, United Kingdom
🇬🇧North Tyneside General Hospital, North Shields, Tyne and Wear, United Kingdom
Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab
- Conditions
- Interventions
- First Posted Date
- 2009-11-09
- Last Posted Date
- 2021-03-30
- Lead Sponsor
- University of South Florida
- Target Recruit Count
- 468
- Registration Number
- NCT01009918
- Locations
- 🇺🇸
Illinois CancerCare - Havana, Havana, Illinois, United States
🇺🇸Saint Luke's Hospital, Chesterfield, Missouri, United States
🇺🇸Illinois CancerCare - Canton, Canton, Illinois, United States
Cardiovascular Prevention for Persons With HIV
- Conditions
- Interventions
- First Posted Date
- 2009-09-23
- Last Posted Date
- 2017-11-22
- Lead Sponsor
- Hennepin Healthcare Research Institute
- Target Recruit Count
- 37
- Registration Number
- NCT00982189
- Locations
- 🇺🇸
Hennepin County Medical Center, Minneapolis, Minnesota, United States
Effect of ACE-inhibitors on Aortic Stiffness in Elderly Patients With Chronic Kidney Disease
- Conditions
- Interventions
- First Posted Date
- 2009-04-02
- Last Posted Date
- 2020-10-27
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 43
- Registration Number
- NCT00874432
- Locations
- 🇺🇸
University of Wisconsin-Madison Hospitals and Clinics, Madison, Wisconsin, United States
Women With Chest Pain and Normal Coronary Arteries Study
- Conditions
- Interventions
- First Posted Date
- 2008-08-28
- Last Posted Date
- 2023-12-12
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 3
- Registration Number
- NCT00743197
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
Black Education and Treatment of Hypertension (BEAT HTN)
- First Posted Date
- 2008-04-21
- Last Posted Date
- 2012-12-04
- Lead Sponsor
- Creighton University
- Target Recruit Count
- 99
- Registration Number
- NCT00661895
- Locations
- 🇺🇸
Creighton Community Health Center, Omaha, Nebraska, United States
The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial
- Conditions
- Interventions
- First Posted Date
- 2008-01-30
- Last Posted Date
- 2013-02-15
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 53
- Registration Number
- NCT00605072
- Locations
- 🇺🇸
Hebrew SeniorLife, Boston, Massachusetts, United States
🇺🇸University of Southern California, Los Angeles, California, United States
Hypertension in Hemodialysis Patients (Aim 3)
- Conditions
- Interventions
- First Posted Date
- 2007-12-28
- Last Posted Date
- 2016-01-18
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 200
- Registration Number
- NCT00582114
- Locations
- 🇺🇸
Indiana University, Indianapolis, Indiana, United States
VA NEPHRON-D: Diabetes iN Nephropathy Study
- Conditions
- Interventions
- First Posted Date
- 2007-11-08
- Last Posted Date
- 2015-05-29
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 1448
- Registration Number
- NCT00555217
- Locations
- 🇺🇸
VA Palo Alto Health Care System, Palo Alto, California, United States
🇵🇷VA Medical Center, San Juan, San Juan, Puerto Rico
🇺🇸VA Medical Center, Memphis, Memphis, Tennessee, United States
Efficacy of Coreg CR and Lisinopril on Markers for Cardiovascular Functional and Structural Disease
- Conditions
- Interventions
- First Posted Date
- 2007-11-06
- Last Posted Date
- 2018-04-24
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 101
- Registration Number
- NCT00553969
- Locations
- 🇺🇸
University of Minnesota, Variety Club Research Center 102, Minneapolis, Minnesota, United States
Drug Development Updates
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