Amantadine
- Generic Name
- Amantadine
- Brand Names
- Gocovri, Osmolex
- Drug Type
- Small Molecule
- Chemical Formula
- C10H17N
- CAS Number
- 768-94-5
- Unique Ingredient Identifier
- BF4C9Z1J53
- Background
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
- Indication
For the chemoprophylaxis, prophylaxis, and treatment of signs and symptoms of infection caused by various strains of influenza A virus. Also for the treatment of parkinsonism and drug-induced extrapyramidal reactions.
- Associated Conditions
- Dyskinesia, Extrapyramidal disorder caused by neuroleptic drugs without Tardive dyskinesia, Influenza A Virus Infection, Parkinson's Disease (PD), Parkinson's Disease With Wearing-off Motor Fluctuations, Parkinsonism
Prepulse Inhibition of Startle in Cocaine Dependence - 7
- Conditions
- Cocaine-Related DisordersSubstance-Related Disorders
- First Posted Date
- 2001-04-18
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00015249
- Locations
- 🇺🇸
New York MDRU, New York, New York, United States
Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4
- Conditions
- Cocaine-Related Disorders
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2016-07-11
- Lead Sponsor
- University of California, Los Angeles
- Registration Number
- NCT00000301
- Locations
- 🇺🇸
Friends Research Institute, Los Angeles, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.