Clopidogrel
- Generic Name
- Clopidogrel
- Brand Names
- Duoplavin, Plavix, Zyllt, Clopidogrel BGR (previously Zylagren), Clopidogrel TAD, Clopidogrel ratiopharm, Clopidogrel Zentiva (previously Clopidogrel Winthrop), Clopidogrel Krka, Clopidogrel Krka d.d. (previously Zopya), Clopidogrel Teva (hydrogen sulphate), Clopidogrel HCS, Iscover, Grepid, Clopidogrel Taw Pharma (previously Clopidogrel Mylan), Clopidogrel Viatris (previously Clopidogrel Taw Pharma)
- Drug Type
- Small Molecule
- Chemical Formula
- C16H16ClNO2S
- CAS Number
- 113665-84-2
- Unique Ingredient Identifier
- A74586SNO7
- Background
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial diseas...
- Indication
1.用于新近心肌梗死、新近脑卒中或确诊的周围动脉病变患者，可减少新的缺血性脑卒中、心肌梗死和死亡等心脑血管事件的符合终点；
2.用于急性冠状动脉综合征（不稳定心绞痛和非ST段抬高心肌梗死）患者；
3.用于冠状动脉支架置入术后预防支架内血栓形成（与阿司匹林联用）。
- Associated Conditions
- Acute Coronary Syndrome (ACS), Acute Myocardial Infarction (AMI), Cardiovascular Events, Atherothrombotic events
- Associated Therapies
- -
The Effect of Clopidogrel on Coated-Platelets in Patients Undergoing Cardiac Catheterization
- Conditions
- First Posted Date
- 2008-03-27
- Last Posted Date
- 2011-10-07
- Lead Sponsor
- University of Oklahoma
- Target Recruit Count
- 27
- Registration Number
- NCT00644657
- Locations
- 🇺🇸
VA Medical Center, 1F187, Oklahoma City, Oklahoma, United States
A Study of the Antiplatelet Effects Comparing Ticagrelor (Ticag. - AZD6140) With Clopidogrel (Clop.) Responder and Non-responders
- Conditions
- Interventions
- First Posted Date
- 2008-03-25
- Last Posted Date
- 2011-10-04
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 98
- Registration Number
- NCT00642811
- Locations
- 🇬🇧
Research Site, Sheffield, United Kingdom
Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)
- Conditions
- Interventions
- First Posted Date
- 2008-03-24
- Last Posted Date
- 2010-02-23
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 35
- Registration Number
- NCT00642174
- Locations
- 🇺🇸
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Oklahoma City, Oklahoma, United States
Doubling the Maintenance Dose of Clopidogrel in Patients With High On-Clopidogrel Platelet Reactivity
- Conditions
- Interventions
- First Posted Date
- 2008-03-19
- Last Posted Date
- 2010-03-23
- Lead Sponsor
- University of Pecs
- Target Recruit Count
- 500
- Registration Number
- NCT00638326
- Locations
- 🇭🇺
Heart Institute, University of Pécs, Dept. of Interventional Cardiology, Pécs, Hungary
STREAM-Strategic Reperfusion (With Tenecteplase and Antithrombotic Treatment) Early After Myocardial Infarction
- Conditions
- Interventions
- First Posted Date
- 2008-02-26
- Last Posted Date
- 2019-08-01
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 1899
- Registration Number
- NCT00623623
- Locations
- 🇮🇹
1123.28.39001A Boehringer Ingelheim Investigational Site, Monza, Italy
🇫🇷1123.28.3329A Boehringer Ingelheim Investigational Site, Aubervilliers Cedex, France
🇫🇷1123.28.3329C Boehringer Ingelheim Investigational Site, Aubervilliers Cedex, France
Safety of High-dose Tirofiban During Coronary Angioplasty
- First Posted Date
- 2007-12-04
- Last Posted Date
- 2011-02-02
- Lead Sponsor
- S. Anna Hospital
- Target Recruit Count
- 2000
- Registration Number
- NCT00566891
- Locations
- 🇮🇹
S Anna Hospital, Catanzaro, Italy
Platelet Function Assessment for Atherothrombotic Patients
- First Posted Date
- 2007-08-08
- Last Posted Date
- 2011-01-24
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 150
- Registration Number
- NCT00513149
- Locations
- 🇨🇳
Division of Cardiology, Department of Internal Medicine and Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
Clopidogrel Reloading in Clopidogrel Resistant Patients With ACS
- Conditions
- First Posted Date
- 2007-03-07
- Last Posted Date
- 2007-09-20
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT00444132
- Locations
- 🇮🇱
ICCU, Sheba Medical Center, Tel-hashomer, Ramat Gan, Israel
H2 Haplotype and CYP3As Polymorphisms and the Antiplatelet Response to Clopidogrel
- Conditions
- First Posted Date
- 2007-02-12
- Last Posted Date
- 2012-08-21
- Lead Sponsor
- Hopital du Sacre-Coeur de Montreal
- Target Recruit Count
- 120
- Registration Number
- NCT00433784
- Locations
- 🇨🇦
Hôpital du Sacré-Coeur de Montréal, Montréal, Quebec, Canada
Clopidogrel Only Before Percutaneous Coronary Intervention or Before Every Coronarography?
- First Posted Date
- 2007-02-07
- Last Posted Date
- 2008-01-29
- Lead Sponsor
- Charles University, Czech Republic
- Registration Number
- NCT00432120
- Locations
- 🇨🇿
Charles University, Prague, Czech Republic
Drug Development Updates
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