Aripiprazole
- Generic Name
- Aripiprazole
- Brand Names
- Abilify, Aripiprazole Mylan Pharma (previously Aripiprazole Pharmathen), Abilify Maintena, Aripiprazole Accord, Aripiprazole Sandoz, Aripiprazole Zentiva
- Drug Type
- Small Molecule
- Chemical Formula
- C23H27Cl2N3O2
- CAS Number
- 129722-12-9
- Unique Ingredient Identifier
- 82VFR53I78
- Background
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A ...
- Indication
Aripiprazole is indicated for the treatment of acute manic and mixed episodes associated with bipolar I disorder, irritability associated with autism spectrum disorder, schizophrenia, and Tourette's disorder. It is also used as an adjunctive treatment of major depressive disorder.[L45859 An injectable formulation of aripiprazole is indicated for agitation as...
- Associated Conditions
- Agitation, Bipolar 1 Disorder, Irritability, Major Depressive Disorder (MDD), Mixed manic depressive episode, Psychosis, Psychotic Depression, Schizophrenia, Tourette's Disorder (TD), Acute Manic episode
- Associated Therapies
- Monotherapy
Biomarkers in Autism of Aripiprazole and Risperidone Treatment (BAART)
- First Posted Date
- 2011-04-11
- Last Posted Date
- 2018-09-26
- Lead Sponsor
- Medical University of South Carolina
- Target Recruit Count
- 80
- Registration Number
- NCT01333072
- Locations
- 🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States
A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients
- First Posted Date
- 2011-04-04
- Last Posted Date
- 2022-09-07
- Lead Sponsor
- Denovo Biopharma LLC
- Target Recruit Count
- 678
- Registration Number
- NCT01328093
- Locations
- 🇸🇪
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Malmo, Sweden
Aripiprazole Effects on Alcohol Drinking and Craving
- First Posted Date
- 2011-02-09
- Last Posted Date
- 2017-08-08
- Lead Sponsor
- Medical University of South Carolina
- Target Recruit Count
- 99
- Registration Number
- NCT01292057
- Locations
- 🇺🇸
Medical University of South Carolina, Institute of Psychiatry, Center for Drug and Alcohol Programs, Charleston, South Carolina, United States
Phase IV Long-term Maintenance Study of Aripiprazole in the Treatment of Irritability Associated With Autistic Disorder
- Conditions
- Interventions
- First Posted Date
- 2010-10-25
- Last Posted Date
- 2014-05-02
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 215
- Registration Number
- NCT01227668
- Locations
- 🇺🇸
Childrens Specialty Gr., Pllc, Norfolk, Virginia, United States
🇺🇸Stony Brook University School Of Medicine, Stony Brook, New York, United States
🇺🇸Children'S Specialized Hosp, Toms River, New Jersey, United States
Twelve Month Study Comparing Paliperidone Palmitate and Select Oral Antipsychotics in Adults With Schizophrenia Who Have Been Recently Discharged From an Inpatient Psychiatric Hospital
- First Posted Date
- 2010-09-01
- Last Posted Date
- 2013-07-08
- Lead Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
- Registration Number
- NCT01193166
Open Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Aripiprazole When Coadministered To Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2010-08-25
- Last Posted Date
- 2011-11-06
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 38
- Registration Number
- NCT01188668
- Locations
- 🇺🇸
Pfizer Investigational Site, Miami, Florida, United States
Evaluation of Negative Symptoms and Cognitive Function After Administration of Antipsychotics in Healthy Volunteer
- Conditions
- Interventions
- First Posted Date
- 2010-08-20
- Last Posted Date
- 2010-08-20
- Lead Sponsor
- Chonbuk National University Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT01185418
- Locations
- 🇰🇷
Chonbuk national university hospital, Jeonju, Korea, Republic of
Clinical Effectiveness of Newer Antipsychotics in Comparison With Conventional Antipsychotics in Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2010-07-16
- Last Posted Date
- 2015-06-22
- Lead Sponsor
- University of Bremen
- Target Recruit Count
- 149
- Registration Number
- NCT01164059
- Locations
- 🇩🇪
Klinikum Bremen-Ost gGmbH, Bremen, Germany
🇩🇪Rheinische Kliniken Düsseldorf der Heinrich-Heine-Universität, Düsseldorf, Germany
🇩🇪Privat-Nerven-Klinik Dr. med. Kurt Fontheim, Liebenburg, Germany
Effects of Aripiprazole and Haloperidol on Mesolimbic System Functioning
- Conditions
- Interventions
- First Posted Date
- 2010-07-13
- Last Posted Date
- 2014-09-12
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 54
- Registration Number
- NCT01161277
- Locations
- 🇳🇴
Oslo University Hospital, Ullevål, Oslo, Norway
15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated
- First Posted Date
- 2010-07-07
- Last Posted Date
- 2015-04-24
- Lead Sponsor
- Janssen Scientific Affairs, LLC
- Target Recruit Count
- 450
- Registration Number
- NCT01157351
Drug Development Updates
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