MedPath

Posizolid

Generic Name
Posizolid
Drug Type
Small Molecule
Chemical Formula
C21H21F2N3O7
CAS Number
252260-06-3
Unique Ingredient Identifier
82V2M8K24R
Background

Posizolid (AZD2563) is an oxazolidinone antibiotic. In July 2002, after completion of phase I trials in December 2001, AstraZeneca announced that they were no longer pursuing the development of Posizolid, presumably due to negative trial results (though no results were reported).

Indication

For the treatment of gram-positive infections, including multiresistant strains.

Phase 2a EBA Trial of AZD5847

Phase 2
Completed
Conditions
Tuberculosis
Interventions
Drug: Ethambutol, isoniazid, pyrazinamide, rifampin
First Posted Date
2012-01-24
Last Posted Date
2018-10-15
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
75
Registration Number
NCT01516203
Locations
🇿🇦

Task Clinical Research Centre, Ekurhuleni, Gauteng, South Africa

A Study in Healthy Volunteers to Assess Safety and Blood Levels of AZD5847 After Multiple Doses Over 14 Days

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
First Posted Date
2010-05-04
Last Posted Date
2010-10-11
Lead Sponsor
AstraZeneca
Target Recruit Count
60
Registration Number
NCT01116258
Locations
🇺🇸

Research Site, Overland Park, Kansas, United States

Study to Evaluate Safety, Tolerability and Pharmacokinetics (PK) (Including Food Effect) of Oral Doses of AZD5847 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo to AZD5847
First Posted Date
2009-12-23
Last Posted Date
2010-07-14
Lead Sponsor
AstraZeneca
Target Recruit Count
64
Registration Number
NCT01037725
Locations
🇺🇸

Research Site, Overland Park, Kansas, United States

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