Glucagon

Generic Name
Glucagon
Brand Names
Baqsimi, Glucagen, Gvoke, Ogluo
Drug Type
Biotech
Chemical Formula
-
CAS Number
16941-32-5
Unique Ingredient Identifier
76LA80IG2G
Background

Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia. Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.
...

Indication

Glucagon is indicated as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.

Associated Conditions
Severe Hypoglycemia
Associated Therapies
-

Glucagon Regulation of Glucose Metabolism

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-04-15
Last Posted Date
2021-05-14
Lead Sponsor
David D'Alessio, M.D.
Target Recruit Count
19
Registration Number
NCT04347252
Locations
🇺🇸

Duke Center for Living, Durham, North Carolina, United States

Dual-hormone Closed-loop Glucose Control in Type 1 Diabetes

First Posted Date
2019-08-12
Last Posted Date
2022-08-18
Lead Sponsor
Steno Diabetes Center Copenhagen
Target Recruit Count
13
Registration Number
NCT04053712
Locations
🇩🇰

Steno Diabetes Center Copenhagen, Gentofte, Denmark

The Effect of Glucagon on Rates of Hepatic Mitochondrial Oxidation in Man Assessed by PINTA

First Posted Date
2019-05-28
Last Posted Date
2024-11-26
Lead Sponsor
Yale University
Target Recruit Count
10
Registration Number
NCT03965130
Locations
🇺🇸

Yale Hospital reserach Unit / YCCI, New Haven, Connecticut, United States

Intranasal Glucagon and Energy Balance

Phase 2
Conditions
Interventions
First Posted Date
2018-08-28
Last Posted Date
2018-08-31
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
20
Registration Number
NCT03650582
Locations
🇨🇦

Toronto General Hospital, Toronto, Ontario, Canada

Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition

First Posted Date
2018-05-23
Last Posted Date
2019-10-17
Lead Sponsor
University Hospital Bispebjerg and Frederiksberg
Target Recruit Count
10
Registration Number
NCT03533179
Locations
🇩🇰

University Hospital Bispebjerg, Copenhagen, Denmark

Hepatic Metabolic Changes in Response to Glucagon Infusion

First Posted Date
2018-05-16
Last Posted Date
2019-08-06
Lead Sponsor
Steno Diabetes Center Copenhagen
Target Recruit Count
27
Registration Number
NCT03526445
Locations
🇩🇰

Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

Glucagon Infusion in T1D Patients With Recurrent Severe Hypoglycemia: Effects on Counter-Regulatory Responses

First Posted Date
2018-04-06
Last Posted Date
2021-02-21
Lead Sponsor
Xeris Pharmaceuticals
Target Recruit Count
49
Registration Number
NCT03490942
Locations
🇺🇸

University of Alabama, Birmingham, Birmingham, Alabama, United States

🇺🇸

University of California, San Diego, San Diego, California, United States

🇺🇸

Emory University - Grady Memorial Hospital, Atlanta, Georgia, United States

and more 2 locations

First Research Study to Compare a Possible New Medicine NNC9204-1513 to the Medicine Glucagon, in Healthy People.

First Posted Date
2018-02-23
Last Posted Date
2018-09-05
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
36
Registration Number
NCT03444467
Locations
🇩🇪

Novo Nordisk Investigational Site, Berlin, Germany

Closed-Loop Glucagon Pump for Treatment of Post-Bariatric Hypoglycemia

First Posted Date
2017-08-21
Last Posted Date
2022-09-06
Lead Sponsor
Joslin Diabetes Center
Target Recruit Count
18
Registration Number
NCT03255629
Locations
🇺🇸

Joslin Diabetes Center, Boston, Massachusetts, United States

Liver Glycogen and Hypoglycemia in Humans

First Posted Date
2017-08-07
Last Posted Date
2024-02-28
Lead Sponsor
Jason Winnick
Target Recruit Count
40
Registration Number
NCT03241706
Locations
🇺🇸

University of Cincinnati, Cincinnati, Ohio, United States

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