Varenicline
- Generic Name
- Varenicline
- Brand Names
- Champix, Chantix, Tyrvaya
- Drug Type
- Small Molecule
- Chemical Formula
- C13H13N3
- CAS Number
- 249296-44-4
- Unique Ingredient Identifier
- W6HS99O8ZO
- Background
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A...
- Indication
For use as an aid in smoking cessation.
Varenicline as a nasal spray is indicated for the symptomatic treatment of dry eye disease.
- Associated Conditions
- Dry Eye Syndrome (DES)
- Associated Therapies
- Smoking, Cessation
Reducing Falls with Varenicline in Hypocholinergic Parkinson Disease
- First Posted Date
- 2024-11-07
- Last Posted Date
- 2024-11-07
- Lead Sponsor
- Vikas Kotagal
- Target Recruit Count
- 102
- Registration Number
- NCT06679374
- Locations
- 🇺🇸
University of Michigan, Ann Arbor, Michigan, United States
Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse
- Conditions
- Interventions
- First Posted Date
- 2024-09-24
- Last Posted Date
- 2024-09-24
- Lead Sponsor
- Yale University
- Target Recruit Count
- 114
- Registration Number
- NCT06609369
- Locations
- 🇺🇸
Yale University, New Haven, Connecticut, United States
The Avenues Study: Dual Use Cessation
- Conditions
- Interventions
- First Posted Date
- 2024-06-25
- Last Posted Date
- 2024-06-25
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 500
- Registration Number
- NCT06474299
- Locations
- 🇺🇸
University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, United States
Tobacco Treatment Comparison for Cancer Care
- First Posted Date
- 2024-01-23
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 52
- Registration Number
- NCT06218823
- Locations
- 🇺🇸
UW Carbone Cancer Center, Madison, Wisconsin, United States
Project HOPES: Healthy Options for Pain and Ending Smoking. A Program for Cancer Survivors.
- Conditions
- Interventions
- First Posted Date
- 2023-09-08
- Last Posted Date
- 2024-10-10
- Lead Sponsor
- Duke University
- Target Recruit Count
- 20
- Registration Number
- NCT06029907
- Locations
- 🇺🇸
Duke University Health System, Durham, North Carolina, United States
Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use
- Conditions
- Interventions
- First Posted Date
- 2023-09-07
- Last Posted Date
- 2024-06-28
- Lead Sponsor
- Yale University
- Target Recruit Count
- 40
- Registration Number
- NCT06027840
- Locations
- 🇺🇸
Yale University, New Haven, Connecticut, United States
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2
- Conditions
- Interventions
- First Posted Date
- 2023-08-23
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- Yale University
- Target Recruit Count
- 30
- Registration Number
- NCT06006143
V+PSF-M for Tobacco Cessation in HIV Care in India
- Conditions
- Interventions
- First Posted Date
- 2023-03-27
- Last Posted Date
- 2024-12-10
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 400
- Registration Number
- NCT05786547
- Locations
- 🇮🇳
VHS Infectious Disease Medical Centre, CART Clinical Research Site, Chennai, Tamil Nadu, India
🇺🇸University of Colorado, Aurora, Colorado, United States
Botswana Smoking and Abstinence Reinforcement Trial
- First Posted Date
- 2023-01-23
- Last Posted Date
- 2024-11-13
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 750
- Registration Number
- NCT05694637
- Locations
- 🇧🇼
Tutume Primary Hospital, Tutume, Central, Botswana
🇧🇼Masego Clinic, Francistown, Central, Botswana
🇧🇼Sefhare Primary Hospital, Sefhare, Central, Botswana
Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes
- Conditions
- Interventions
- First Posted Date
- 2022-12-08
- Last Posted Date
- 2024-04-29
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 400
- Registration Number
- NCT05642715
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.