Nebivolol
- Generic Name
- Nebivolol
- Brand Names
- Bystolic
- Drug Type
- Small Molecule
- Chemical Formula
- C22H25F2NO4
- CAS Number
- 118457-14-0
- Unique Ingredient Identifier
- 030Y90569U
- Background
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta blockers are generally not first l...
- Indication
Nebivolol is indicated to treat hypertension.
- Associated Conditions
- Hypertension
- Associated Therapies
- -
Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients
- First Posted Date
- 2012-01-02
- Last Posted Date
- 2020-07-07
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 46
- Registration Number
- NCT01502787
- Locations
- 🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States
Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
- First Posted Date
- 2011-12-30
- Last Posted Date
- 2018-11-06
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 32
- Registration Number
- NCT01501929
- Locations
- 🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States
Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure
- Conditions
- Interventions
- First Posted Date
- 2011-12-26
- Last Posted Date
- 2014-12-17
- Lead Sponsor
- Thomas Jefferson University
- Target Recruit Count
- 17
- Registration Number
- NCT01499134
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
The Impact of Nebivolol Versus Metoprolol on Quality of Life
- Conditions
- Interventions
- First Posted Date
- 2011-09-27
- Last Posted Date
- 2017-04-20
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 11
- Registration Number
- NCT01441570
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸Lahey Clinic, Burlington, Massachusetts, United States
Study of the Efficacy and Safety of Nebivolol in Younger Patients (18 - 54 Years)
- First Posted Date
- 2011-08-12
- Last Posted Date
- 2013-05-16
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 641
- Registration Number
- NCT01415531
- Locations
- 🇺🇸
Forest Investigative Site 011, Raleigh, North Carolina, United States
🇺🇸Forest Investigative Site 065, Phoenix, Arizona, United States
🇺🇸Forest Investigative Site 067, Phoenix, Arizona, United States
Nebivolol and the Endothelin (ET)-1 System
- Conditions
- Interventions
- First Posted Date
- 2011-07-15
- Last Posted Date
- 2019-01-02
- Lead Sponsor
- University of Colorado, Boulder
- Target Recruit Count
- 42
- Registration Number
- NCT01395329
- Locations
- 🇺🇸
UC-Boulder Clinical and Translational Research Center, Boulder, Colorado, United States
Regression of Myocardial Steatosis by Nebivolol
- First Posted Date
- 2011-05-23
- Last Posted Date
- 2017-07-14
- Lead Sponsor
- Lidia Szczepaniak
- Target Recruit Count
- 31
- Registration Number
- NCT01358409
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
Effects of Nebivolol Versus Metoprolol Succinate on Endothelial Function
- First Posted Date
- 2010-11-25
- Last Posted Date
- 2010-11-25
- Lead Sponsor
- Berlin-Chemie AG Menarini Group
- Target Recruit Count
- 80
- Registration Number
- NCT01248338
- Locations
- 🇪🇪
Cardiology Clinic of Tartu University Clinics, Tartu, Estonia
Evaluation of The Effects of Nebivolol in Comparison to Atenolol on Wall Shear Stress and Rupture Prone Coronary Plaques
- Conditions
- Interventions
- First Posted Date
- 2010-10-29
- Last Posted Date
- 2015-02-27
- Lead Sponsor
- Emory University
- Target Recruit Count
- 29
- Registration Number
- NCT01230892
- Locations
- 🇺🇸
Emory University Hospital, Atlanta, Georgia, United States
An Advanced Echocardiographic Evaluation of Nebivolol
- First Posted Date
- 2010-09-21
- Last Posted Date
- 2018-02-15
- Lead Sponsor
- Jack Rubinstein
- Target Recruit Count
- 2
- Registration Number
- NCT01206439
- Locations
- 🇺🇸
University of Cincinnati, Cincinnati, Ohio, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.