Nebivolol
- Generic Name
- Nebivolol
- Brand Names
- Bystolic
- Drug Type
- Small Molecule
- Chemical Formula
- C22H25F2NO4
- CAS Number
- 118457-14-0
- Unique Ingredient Identifier
- 030Y90569U
- Background
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta blockers are generally not first l...
- Indication
Nebivolol is indicated to treat hypertension.
- Associated Conditions
- Hypertension
- Associated Therapies
- -
Nebivolol Versus Metoprolol: Comparative Effects on Fatigue and Quality of Life
- First Posted Date
- 2009-10-21
- Last Posted Date
- 2018-10-19
- Lead Sponsor
- Weill Medical College of Cornell University
- Target Recruit Count
- 37
- Registration Number
- NCT00999102
- Locations
- 🇺🇸
Weill Cornell Medical College, New York, New York, United States
Nebivolol Versus Metoprolol: Sodium Sensitivity
- First Posted Date
- 2009-10-08
- Last Posted Date
- 2017-06-08
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 24
- Registration Number
- NCT00992056
- Locations
- 🇺🇸
Division of Clinical Pharmacology Clinical Pharmacology Research Unit (CPRU) 1500 NW 12th Ave 15-West., Miami, Florida, United States
Effects of Nebivolol Versus Carvedilol on Cardiopulmonary Function at High Altitude in Healthy Subjects.
- Conditions
- Interventions
- First Posted Date
- 2009-06-19
- Last Posted Date
- 2009-09-02
- Lead Sponsor
- Istituto Auxologico Italiano
- Target Recruit Count
- 27
- Registration Number
- NCT00924833
- Locations
- 🇮🇹
Laboratorio Ricerche Cardiologiche. Istituto Auxologico Italiano. Ospedale S. Luca. Via Spagnoletto, 3. Regina Margherita Hut (Monte Rosa, Italian Alps, 4559 m), Milan, Italy
Alternative in Beta Blocker Intolerance: The ABBI Trial
- First Posted Date
- 2009-05-06
- Last Posted Date
- 2019-08-06
- Lead Sponsor
- Minneapolis Heart Institute Foundation
- Target Recruit Count
- 6
- Registration Number
- NCT00893984
- Locations
- 🇺🇸
Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, Minnesota, United States
Comparing the Effects of Two Beta Blockers,Metoprolol and Nebivolol,on Ambulatory Blood Pressure and Basal Metabolic Rate
- First Posted Date
- 2009-02-24
- Last Posted Date
- 2013-03-19
- Lead Sponsor
- University of Mississippi Medical Center
- Target Recruit Count
- 1
- Registration Number
- NCT00849810
- Locations
- 🇺🇸
University of Mississippi Medical Center, Jackson, Mississippi, United States
Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries
- First Posted Date
- 2009-01-27
- Last Posted Date
- 2016-02-05
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 70
- Registration Number
- NCT00829296
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
A Study on the Long-term Efficacy of Nebivolol After Withdrawal of Therapy
- First Posted Date
- 2008-11-05
- Last Posted Date
- 2010-09-15
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 207
- Registration Number
- NCT00785512
- Locations
- 🇺🇸
Forest Investigative Site, Dallas, Texas, United States
Comparative Effect of Nebivolol vs. Metoprolol on Insulin Sensitivity and Fibrinolytic Balance in Metabolic Syndrome
- Conditions
- Interventions
- First Posted Date
- 2008-10-20
- Last Posted Date
- 2012-10-23
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 46
- Registration Number
- NCT00775671
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
A Study on the Efficacy and Safety of Nebivolol Monotherapy in Hispanic Hypertensive Patients
- First Posted Date
- 2008-10-10
- Last Posted Date
- 2011-01-26
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 277
- Registration Number
- NCT00770861
- Locations
- 🇵🇷
Forest Investigative Site, Santurce, Puerto Rico
🇺🇸Forest Investigative Site FL2, Hialeah, Florida, United States
Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients
- Conditions
- Interventions
- First Posted Date
- 2008-08-29
- Last Posted Date
- 2011-07-29
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 231
- Registration Number
- NCT00744237
- Locations
- 🇺🇸
Forest Investigative Site 49, Tustin, California, United States
🇺🇸Forest Investigative Site 32, Pembroke Pines, Florida, United States
🇺🇸Forest Investigative Site 081, Pembroke Pines, Florida, United States
Drug Development Updates
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