FN-1501

Generic Name
FN-1501
Brand Names
Cellcept, Myfenax, CellCept, Mycophenolate mofetil Teva, Myclausen
Drug Type
Small Molecule
Chemical Formula
C22H25N9O
CAS Number
1429515-59-2
Unique Ingredient Identifier
6MC966B505
Background

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is markete...

Indication

Mycophenolate mofetil is indicated in combination with other immunosuppressants to prevent the rejection of kidney, heart, or liver transplants in adult and pediatric patients ≥3 months old. Mycophenolate mofetil may also be used off-label as a second-line treatment for autoimmune hepatitis that has not responded adequately to first-line therapy. Other off-l...

Associated Conditions
Transplanted Organ Rejection
Associated Therapies
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Evaluation of Rovadicitinib Compared to the Protocol Selected by Researchers in Third Line and Subsequent Studies of Moderate to Severe Chronic Graft-versus-host Disease

First Posted Date
2024-11-12
Last Posted Date
2024-11-26
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
182
Registration Number
NCT06682169
Locations
🇨🇳

The First Affiliated Hospital of USTC Anhui Provincial Hospital, Hefei, Anhui, China

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

First Posted Date
2024-11-08
Last Posted Date
2024-11-08
Lead Sponsor
Leland Metheny
Target Recruit Count
20
Registration Number
NCT06680661
Locations
🇺🇸

University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Short-term Glucocorticoid Combined with MMF for IgG4-RD

Not Applicable
Recruiting
Conditions
Interventions
First Posted Date
2024-10-29
Last Posted Date
2024-10-29
Lead Sponsor
Wen Zhang
Target Recruit Count
63
Registration Number
NCT06663618
Locations
🇨🇳

Peking Union Medical College Hospital, Beijing, Beijing, China

Efficacy and Safety of Telitacicept in the Treatment of Systemic Sclerosis

First Posted Date
2024-04-19
Last Posted Date
2024-04-19
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Target Recruit Count
38
Registration Number
NCT06375005
Locations
🇨🇳

Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, China

🇨🇳

Huashan Hospital of Fudan University, Shanghai, Shanghai, China

🇨🇳

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

and more 6 locations

Treatment FOr Corticosteroid Dependent UveitiS

Phase 3
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-02-14
Last Posted Date
2024-02-14
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
120
Registration Number
NCT06258915

Comparative Efficacy of Mizoribine With Mycophenolate Mofetil for Living Related Kidney Transplantation Recipients

First Posted Date
2023-11-02
Last Posted Date
2023-11-02
Lead Sponsor
Lee's Pharmaceutical Limited
Target Recruit Count
152
Registration Number
NCT06114953
Locations
🇨🇳

Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China

🇨🇳

First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

🇨🇳

The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China

and more 3 locations

Advancing Transplantation Outcomes in Children

First Posted Date
2023-09-28
Last Posted Date
2024-12-10
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
200
Registration Number
NCT06055608
Locations
🇺🇸

University of Alabama at Birmingham (Site # 71038), Birmingham, Alabama, United States

🇺🇸

Children's Hospital of Los Angeles (Site #: 71036), Los Angeles, California, United States

🇺🇸

Cedars-Sinai Medical Center (Site #: 71026), Los Angeles, California, United States

and more 18 locations
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