FN-1501

Generic Name
FN-1501
Brand Names
Cellcept, Myfenax, CellCept, Mycophenolate mofetil Teva, Myclausen
Drug Type
Small Molecule
Chemical Formula
C22H25N9O
CAS Number
1429515-59-2
Unique Ingredient Identifier
6MC966B505
Background

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is markete...

Indication

Mycophenolate mofetil is indicated in combination with other immunosuppressants to prevent the rejection of kidney, heart, or liver transplants in adult and pediatric patients ≥3 months old. Mycophenolate mofetil may also be used off-label as a second-line treatment for autoimmune hepatitis that has not responded adequately to first-line therapy. Other off-l...

Associated Conditions
Transplanted Organ Rejection
Associated Therapies
-
Clinical Trials
Related News

Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant

First Posted Date
2021-09-02
Last Posted Date
2024-10-14
Lead Sponsor
Thomas Jefferson University
Target Recruit Count
63
Registration Number
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Locations
🇺🇸

Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania, United States

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

First Posted Date
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Last Posted Date
2024-11-25
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Target Recruit Count
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Registration Number
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Locations
🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

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National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe)

First Posted Date
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Last Posted Date
2024-05-07
Lead Sponsor
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Registration Number
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Locations
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HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

First Posted Date
2021-05-27
Last Posted Date
2024-05-23
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Center for International Blood and Marrow Transplant Research
Target Recruit Count
300
Registration Number
NCT04904588
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Ohio State Medical Center, James Cancer Center, Columbus, Ohio, United States

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Selective CD28 Blockade in Renal Transplant Recipients

First Posted Date
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Last Posted Date
2023-03-22
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Registration Number
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Locations
🇺🇸

Emory University Hospital, Atlanta, Georgia, United States

Methods of T Cell Depletion Trial (MoTD)

First Posted Date
2021-05-17
Last Posted Date
2023-09-28
Lead Sponsor
University of Birmingham
Target Recruit Count
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Registration Number
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Locations
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Queen Elizabeth Hospital, Birmingham, United Kingdom

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Bristol Haematology and Oncology Centre, Bristol, United Kingdom

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University Hospital of Wales, Cardiff, Wales, United Kingdom

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A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

First Posted Date
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Last Posted Date
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Registration Number
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Locations
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Local Institution - 0038, Seattle, Washington, United States

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Local Institution - 0045, Miami, Florida, United States

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Local Institution - 0022, Hollywood, Florida, United States

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Pharmacokinetics and Pharmacodynamics of Mycophenolate Mofetil in Pediatric Hematopoietic Stem Cell Transplantation

First Posted Date
2021-05-03
Last Posted Date
2023-02-06
Lead Sponsor
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Target Recruit Count
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Registration Number
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Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

Belatacept With Early Steroid Withdrawal rATG and Everolimus in Renal Transplantation (BETTER Trial)

First Posted Date
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Last Posted Date
2021-04-19
Lead Sponsor
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Registration Number
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Locations
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The Christ Hospital, Cincinnati, Ohio, United States

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University of Cincinnati, Cincinnati, Ohio, United States

Treatment Efficacy of Corticosteroids and Mycophenolate Mofetil in Patients With Immune Related Hepatitis

First Posted Date
2021-03-22
Last Posted Date
2022-12-14
Lead Sponsor
Inge Marie Svane
Target Recruit Count
60
Registration Number
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Locations
🇩🇰

Aarhus University Hospital, Aarhus, Denmark

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Odense University Hospital, Odense, Denmark

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Herlev University Hospital, Herlev, Copenhagen, Denmark

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