Nesiritide

Generic Name
Nesiritide
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
124584-08-3
Unique Ingredient Identifier
P7WI8UL647
Background

Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.

Indication

适用于急性代偿性心力衰竭、慢性失代偿性心力衰竭、心肌梗死、心脏导管手术等。由于静脉使用起效快,更适用于急性心力衰竭。

Associated Conditions
Acute Decompensated Heart Failure (ADHF)
Associated Therapies
-

Nesiritide for Ventilated Congestive Heart Failure

First Posted Date
2020-07-02
Last Posted Date
2020-07-02
Lead Sponsor
Shanghai Zhongshan Hospital
Target Recruit Count
30
Registration Number
NCT04455477
Locations
🇨🇳

Zhongshan Hospital, Xuhui, Shanghai, China

Early rhBNP on Myocardial Work in Patients With STEMI

First Posted Date
2019-11-08
Last Posted Date
2019-11-08
Lead Sponsor
RenJi Hospital
Target Recruit Count
200
Registration Number
NCT04157868

Early rhBNP on Myocardial Remodeling and Reperfusion in Patients With STEMI

First Posted Date
2019-07-26
Last Posted Date
2023-06-01
Lead Sponsor
RenJi Hospital
Target Recruit Count
352
Registration Number
NCT04033861
Locations
🇨🇳

Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University, Shanghai, China

Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1

First Posted Date
2018-11-13
Last Posted Date
2024-03-05
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
32
Registration Number
NCT03738878
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Impact of Nesiritide on Early Postoperative Recovery After Total Cavo-Pulmonary Connection Surgery in Children

First Posted Date
2017-07-02
Last Posted Date
2017-07-06
Lead Sponsor
China National Center for Cardiovascular Diseases
Target Recruit Count
108
Registration Number
NCT03207295
Locations
🇨🇳

Fuwai hospital, Beijing, Beijing, China

Acute Effects of rhBNP in Patients With PH Associated With Acute Exacerbation of Chronic Pulmonary Disease

Phase 4
Completed
Conditions
Interventions
First Posted Date
2016-04-19
Last Posted Date
2019-10-01
Lead Sponsor
LI ZHAO
Target Recruit Count
9
Registration Number
NCT02742909
Locations
🇨🇳

Shenjing Hospital, Shenyang, Liaoning, China

Natriuretic Peptides and Metabolic Risk in Obesity

Early Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2015-12-30
Last Posted Date
2017-11-06
Lead Sponsor
Vanderbilt University Medical Center
Registration Number
NCT02642523

Nesiritide in Hypertension

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2015-11-20
Last Posted Date
2018-01-03
Lead Sponsor
Oslo University Hospital
Target Recruit Count
15
Registration Number
NCT02608996
Locations
🇳🇴

Akershus University Hospital, Strømmen, Norway

🇳🇴

Oslo University Hospital, Ullevål Hospital, Oslo, Norway

🇳🇴

Oslo University Hopital, Rikshospitalet, Oslo, Norway

Testosterone Regulation of the Natriuretic Peptide System

First Posted Date
2014-10-20
Last Posted Date
2017-10-19
Lead Sponsor
Massachusetts General Hospital
Registration Number
NCT02269072

BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects

First Posted Date
2013-11-07
Last Posted Date
2018-02-14
Lead Sponsor
AdventHealth Translational Research Institute
Target Recruit Count
4
Registration Number
NCT01977859
Locations
🇺🇸

Translational Research Institute for Metabolism and Diabetes, Orlando, Florida, United States

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