Nesiritide
- Generic Name
- Nesiritide
- Drug Type
- Biotech
- CAS Number
- 124584-08-3
- Unique Ingredient Identifier
- P7WI8UL647
- Background
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
- Indication
适用于急性代偿性心力衰竭、慢性失代偿性心力衰竭、心肌梗死、心脏导管手术等。由于静脉使用起效快，更适用于急性心力衰竭。
- Associated Conditions
- Acute Decompensated Heart Failure (ADHF)
FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for Hospitalization.
- Conditions
- Heart Failure, Congestive
- Interventions
- Drug: usual long term cardiac medications
- First Posted Date
- 2005-12-26
- Last Posted Date
- 2011-07-26
- Lead Sponsor
- Scios, Inc.
- Target Recruit Count
- 214
- Registration Number
- NCT00270361
A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.
- Conditions
- Symptomatic Decompensated Congestive Heart FailureCongestive Heart Failure in Acute Coronary Syndrome
- Interventions
- First Posted Date
- 2005-12-26
- Last Posted Date
- 2011-06-10
- Lead Sponsor
- Scios, Inc.
- Target Recruit Count
- 498
- Registration Number
- NCT00270374
A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure
- First Posted Date
- 2005-12-26
- Last Posted Date
- 2011-06-10
- Lead Sponsor
- Scios, Inc.
- Target Recruit Count
- 255
- Registration Number
- NCT00270400
BELIEVE Study: Nesiritide and Post Myocardial Infarction Left Ventricular Modeling
- Conditions
- Myocardial Infarction
- First Posted Date
- 2005-11-11
- Last Posted Date
- 2009-12-11
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 24
- Registration Number
- NCT00252213
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Nesiritide and Vo2 Max in Heart Failure Patients
- First Posted Date
- 2005-10-17
- Last Posted Date
- 2013-06-19
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 20
- Registration Number
- NCT00240084
- Locations
- 🇺🇸
University of Rochester Medical Center, Rochester, New York, United States
Catheterization Laboratory Study: Acute Responses in Diastolic Heart Failure
- Conditions
- Heart Failure, Congestive
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2019-02-08
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 15
- Registration Number
- NCT00204945
- Locations
- 🇺🇸
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States
Natrecor for Pulmonary Hypertension in Lung Transplants
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2015-10-14
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 7
- Registration Number
- NCT00205426
- Locations
- 🇺🇸
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States
Brain Natriuretic Peptide (BNP) to Preserve Renal Function in Hospitalized Patients With Heart Failure
- Conditions
- Kidney DiseasesCongestive Heart FailureCardiomyopathy
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2009-11-16
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 104
- Registration Number
- NCT00170183
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Effects of Nesiritide in Pediatric Patients With Heart Failure
- Conditions
- Heart FailureVentricular DysfunctionHeart Decompensation
- Interventions
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2014-06-05
- Lead Sponsor
- Emory University
- Registration Number
- NCT00166010
Nesiritide Infusion for the Treatment of Decompensated Heart Failure and Renal Dysfunction
- First Posted Date
- 2005-07-14
- Last Posted Date
- 2013-09-12
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 34
- Registration Number
- NCT00119691
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Drug Development Updates
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