Ezetimibe and Simvastatin
- Generic Name
- Ezetimibe and Simvastatin
- Brand Names
- -
- Drug Type
- -
- Chemical Formula
- -
- CAS Number
- -
- Unique Ingredient Identifier
- -
- Indication
⑴原发性高胆固醇血症：适用于原发性（杂合子家族性或非家族性）高胆固醇血症或混合性高脂血症患者饮食控制以外的辅助治疗。本品可降低总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、载脂蛋白B（Apo B）、甘油三酯（TG）和非高密度脂蛋白胆固醇（non-HDL-C）水平，并能升高高密度脂蛋白胆固醇（HDL-C）水平。
⑵纯合子家族性高胆固醇血症（HoFH）：适用于降低HoFH 患者的TC和LDL-C水平。 本品可作为其他降脂治疗（例如LDL血浆分离置换法）的辅助疗法；或其他降脂治疗无效时用于降低HoFH患者的TC和LDL-C水平。
- Associated Conditions
- -
- Associated Therapies
- -
Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
- First Posted Date
- 2024-05-31
- Last Posted Date
- 2024-10-08
- Lead Sponsor
- Cedars-Sinai Medical Center
- Target Recruit Count
- 140
- Registration Number
- NCT06437574
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
Vascular and Metabolic Effects of Vytorin vs Simvastatin
- Conditions
- Interventions
- First Posted Date
- 2012-08-16
- Last Posted Date
- 2014-11-04
- Lead Sponsor
- Gachon University Gil Medical Center
- Target Recruit Count
- 204
- Registration Number
- NCT01666067
- Locations
- 🇰🇷
Gil Medical Center, Incheon, Korea, Republic of
Vascular and Metabolic Effects of Vytorin
- First Posted Date
- 2012-08-09
- Last Posted Date
- 2014-11-04
- Lead Sponsor
- Gachon University Gil Medical Center
- Target Recruit Count
- 204
- Registration Number
- NCT01660945
- Locations
- 🇰🇷
Gil Medical Center, Incheon, Korea, Republic of
Vytorin in the Treatment of Alopecia Areata
- First Posted Date
- 2012-01-27
- Last Posted Date
- 2015-03-17
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 29
- Registration Number
- NCT01520077
- Locations
- 🇺🇸
University of Miami, Miami, Florida, United States
To Study the Effect of Vytorin on Intracellular Lipid and Inflammation in Obese Subjects
- First Posted Date
- 2011-08-19
- Last Posted Date
- 2024-04-17
- Lead Sponsor
- University at Buffalo
- Target Recruit Count
- 20
- Registration Number
- NCT01420328
- Locations
- 🇺🇸
Diabetes Endocrinology Center of WNY, Buffalo, New York, United States
Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome.
- Conditions
- Interventions
- First Posted Date
- 2009-10-02
- Last Posted Date
- 2023-11-30
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 30
- Registration Number
- NCT00988364
- Locations
- 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol
- First Posted Date
- 2008-09-30
- Last Posted Date
- 2013-07-03
- Lead Sponsor
- Bronx VA Medical Center
- Target Recruit Count
- 34
- Registration Number
- NCT00762164
- Locations
- 🇺🇸
Bronx VA Medical Center, Bronx, New York, United States
Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2)
- Conditions
- Interventions
- First Posted Date
- 2008-04-03
- Last Posted Date
- 2022-02-16
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 18
- Registration Number
- NCT00652431
Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both
- Conditions
- First Posted Date
- 2007-04-18
- Last Posted Date
- 2007-04-18
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 240
- Registration Number
- NCT00461968
- Locations
- 🇺🇸
UT Southwestern Medical Center at Dallas, Dallas, Texas, United States
Drug Development Updates
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