Ezetimibe and Simvastatin
- Generic Name
- Ezetimibe and Simvastatin
- Indication
⑴原发性高胆固醇血症：适用于原发性（杂合子家族性或非家族性）高胆固醇血症或混合性高脂血症患者饮食控制以外的辅助治疗。本品可降低总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、载脂蛋白B（Apo B）、甘油三酯（TG）和非高密度脂蛋白胆固醇（non-HDL-C）水平，并能升高高密度脂蛋白胆固醇（HDL-C）水平。
⑵纯合子家族性高胆固醇血症（HoFH）：适用于降低HoFH 患者的TC和LDL-C水平。 本品可作为其他降脂治疗（例如LDL血浆分离置换法）的辅助疗法；或其他降脂治疗无效时用于降低HoFH患者的TC和LDL-C水平。
Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
- First Posted Date
- 2024-05-31
- Last Posted Date
- 2025-02-27
- Lead Sponsor
- Cedars-Sinai Medical Center
- Target Recruit Count
- 140
- Registration Number
- NCT06437574
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males
- Conditions
- Acute Kidney Injury
- Interventions
- First Posted Date
- 2015-09-11
- Last Posted Date
- 2016-05-03
- Lead Sponsor
- Complexa, Inc.
- Target Recruit Count
- 10
- Registration Number
- NCT02547402
- Locations
- 🇺🇸
Jasper Clinical Research & Development, Inc., Kalamazoo, Michigan, United States
Statins for Oxidative Stress and Mitochondrial Function in Diabetic Polyneuropathy
- Conditions
- Oxidative StressDiabetic Polyneuropathy
- Interventions
- First Posted Date
- 2014-05-02
- Last Posted Date
- 2014-05-06
- Lead Sponsor
- University of Guadalajara
- Target Recruit Count
- 74
- Registration Number
- NCT02129231
- Locations
- 🇲🇽
Cardiovascular Research Unit, Guadalajara, Jalisco, Mexico
Vascular and Metabolic Effects of Vytorin vs Simvastatin
- Conditions
- Hypercholesterolemia
- Interventions
- First Posted Date
- 2012-08-16
- Last Posted Date
- 2014-11-04
- Lead Sponsor
- Gachon University Gil Medical Center
- Target Recruit Count
- 204
- Registration Number
- NCT01666067
- Locations
- 🇰🇷
Gil Medical Center, Incheon, Korea, Republic of
Vascular and Metabolic Effects of Vytorin
- First Posted Date
- 2012-08-09
- Last Posted Date
- 2014-11-04
- Lead Sponsor
- Gachon University Gil Medical Center
- Target Recruit Count
- 204
- Registration Number
- NCT01660945
- Locations
- 🇰🇷
Gil Medical Center, Incheon, Korea, Republic of
A Study to Evaluate the Efficacy and Safety of Vytorin Versus Standard Treatment of Other Statins in Moderate, Moderately High and High Risk Participants (MK-0653A-406)
- First Posted Date
- 2012-04-30
- Last Posted Date
- 2022-02-18
- Lead Sponsor
- Organon and Co
- Registration Number
- NCT01587235
Vytorin in the Treatment of Alopecia Areata
- First Posted Date
- 2012-01-27
- Last Posted Date
- 2015-03-17
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 29
- Registration Number
- NCT01520077
- Locations
- 🇺🇸
University of Miami, Miami, Florida, United States
To Study the Effect of Vytorin on Intracellular Lipid and Inflammation in Obese Subjects
- First Posted Date
- 2011-08-19
- Last Posted Date
- 2024-04-17
- Lead Sponsor
- University at Buffalo
- Target Recruit Count
- 20
- Registration Number
- NCT01420328
- Locations
- 🇺🇸
Diabetes Endocrinology Center of WNY, Buffalo, New York, United States
Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome.
- Conditions
- Metabolic Syndrome
- Interventions
- First Posted Date
- 2009-10-02
- Last Posted Date
- 2023-11-30
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 30
- Registration Number
- NCT00988364
- Locations
- 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)
- Conditions
- Atherosclerosis
- Interventions
- First Posted Date
- 2009-06-23
- Last Posted Date
- 2015-03-18
- Lead Sponsor
- Korea University
- Registration Number
- NCT00926055
- Locations
- 🇰🇷
Korea University Guro, Seoul, Korea, Republic of
Drug Development Updates
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