Icodextrin

Generic Name
Icodextrin
Brand Names
Extraneal
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
337376-15-5
Unique Ingredient Identifier
2NX48Z0A9G
Background

Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via...

Indication

Used for continuous ambulatory peritoneal dialysis (CAPD) of diabetic patients or automated peritoneal dialysis (APD) for the management of end-stage renal disease.

Associated Conditions
-
Associated Therapies
Dialysis therapy

Pharmacokinetics of Single- and Double-dose Icodextrin

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-08-14
Last Posted Date
2024-08-14
Lead Sponsor
Peking University First Hospital
Target Recruit Count
16
Registration Number
NCT06552546
Locations
🇨🇳

Peking University First Hospital, Beijing, Beijing, China

Does Icodextrin Reduce the Risk of Small Bowel Obstruction?

Not Applicable
Conditions
Interventions
First Posted Date
2014-12-17
Last Posted Date
2020-03-31
Lead Sponsor
Uppsala University
Target Recruit Count
1808
Registration Number
NCT02318888
Locations
🇸🇪

Torsby Hospital, Torsby, Sweden

🇸🇪

Jönköping Hospital, Jönköping, Sweden

🇸🇪

Karlstad Hospital, Karlstad, Sweden

and more 10 locations

Efficacy and Safety of a Double Icodextrin Dose in Elderly Incident CAPD Patients on Incremental PD.

Phase 4
Completed
Conditions
Interventions
First Posted Date
2013-09-18
Last Posted Date
2020-11-10
Lead Sponsor
Pr Eric Goffin
Target Recruit Count
117
Registration Number
NCT01944852
Locations
🇧🇪

Cliniques Universitaires Saint-Luc, Brussels, Belgium

Use of a Bimodal Solution for Peritoneal Dialysis

First Posted Date
2010-11-17
Last Posted Date
2017-08-28
Lead Sponsor
Lawson Health Research Institute
Target Recruit Count
36
Registration Number
NCT01242904
Locations
🇨🇦

London Health Sciences Centre, South Street Hospital, Peritoneal Dialysis Unit, London, Ontario, Canada

Peritoneal Dialysis in Congestive Heart Failure

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2010-05-17
Last Posted Date
2019-08-16
Lead Sponsor
Martini Hospital Groningen
Target Recruit Count
26
Registration Number
NCT01124227
Locations
🇳🇱

Martini Hospital, Groningen, Netherlands

Effect of Icodextrin on the Treatment Outcome of Peritoneal Dialysis Patients During Acute Peritonitis

First Posted Date
2010-01-07
Last Posted Date
2016-08-10
Lead Sponsor
Chinese University of Hong Kong
Target Recruit Count
56
Registration Number
NCT01044446
Locations
🇭🇰

Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong

Efficacy and Safety of a 7.5% Icodextrin Peritoneal Dialysis Solution in Once-Daily Long Dwell Exchange

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-07-30
Last Posted Date
2008-08-01
Lead Sponsor
Shanghai Jiao Tong University School of Medicine
Target Recruit Count
2
Registration Number
NCT00725517

IMPENDIA- PEN VS Dianeal Only Improved Metabolic Control In Diabetic CAPD and APD Patients

First Posted Date
2007-12-05
Last Posted Date
2019-06-03
Lead Sponsor
Baxter Healthcare Corporation
Target Recruit Count
137
Registration Number
NCT00567489
Locations
🇭🇰

Prince of Wales Hospital Chinese University of Hong Kong, Sha Tin, N.t., Hong Kong

🇰🇷

Kyungpook National University Hospital, Chung-Gu, Deagu, Korea, Republic of

🇰🇷

Yeungnam University Medical Center, Nam-gu, Deagu, Korea, Republic of

and more 16 locations

IMPENDIA- PEN VS Dianeal Only Improved Metabolic Control In Diabetic CAPD and APD Patients

First Posted Date
2007-12-05
Last Posted Date
2019-06-03
Lead Sponsor
Baxter Healthcare Corporation
Target Recruit Count
43
Registration Number
NCT00567398
Locations
🇦🇺

Westmead Hospital, Sydney, New South Wales, Australia

🇦🇺

Gold Coast Hospital, South Port, Australia

🇨🇦

University Health Network, Toronto General Hospital, Toronto, Ontario, Canada

and more 13 locations

Heart Failure and Peritoneal Ultrafiltration

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2006-08-25
Last Posted Date
2017-05-22
Lead Sponsor
Baxter Healthcare Corporation
Target Recruit Count
12
Registration Number
NCT00368641
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