426c Mod Core-C4b
- Generic Name
- 426c Mod Core-C4b
Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health
Phase 1
Recruiting
- Conditions
- HIV
- Interventions
- Biological: HxB2.WT.Core-C4bBiological: 3M-052-AF adjuvantOther: Aluminum hydroxide suspension (Alum) adjuvantOther: Diluent
- First Posted Date
- 2025-03-25
- Last Posted Date
- 2025-03-27
- Target Recruit Count
- 42
- Registration Number
- NCT06796686
- Locations
- ๐บ๐ธ
Bridge HIV, San Francisco Department of Public Health, San Francisco, California, United States
๐บ๐ธPonce de Leon Center CRS, Atlanta, Georgia, United States
๐บ๐ธThe Hope Clinic of the Emory Vaccine Research Center; Emory University, Decatur, Georgia, United States
Safety & Immunogenicity of 426c.Mod.Core-C4b Vaccine With 3M-052-AF+Alum in Infants Perinatally Exposed to HIV But Uninfected
Phase 1
Not yet recruiting
- Conditions
- HIV Infections
- Interventions
- Biological: Placebo and DiluentBiological: 3M-052-AF
- First Posted Date
- 2024-09-26
- Last Posted Date
- 2025-02-24
- Lead Sponsor
- HIV Vaccine Trials Network
- Target Recruit Count
- 22
- Registration Number
- NCT06613789
- Locations
- ๐ฟ๐ฆ
Soweto HVTN CRS, Soweto, Gauteng, South Africa
The Study of Immunization in People Living With HIV Undergoing an ATI for Elicitation of VRC01-lineage Antibodies
Phase 1
Recruiting
- Conditions
- Chronic HIV Infection
- Interventions
- Other: Adjuvant 3M-052-AF+Alum
- First Posted Date
- 2023-08-23
- Last Posted Date
- 2024-12-13
- Target Recruit Count
- 40
- Registration Number
- NCT06006546
- Locations
- ๐บ๐ธ
New York Blood Center CRS (Site #31801), New York, New York, United States
๐บ๐ธBirmingham, Birmingham, Alabama, United States
๐บ๐ธAtlanta- Ponce, Atlanta, Georgia, United States
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