Etonogestrel

Generic Name
Etonogestrel
Brand Names
Eluryng, Enilloring, Implanon, Nexplanon, Nuvaring
Drug Type
Small Molecule
Chemical Formula
C22H28O2
CAS Number
54048-10-1
Unique Ingredient Identifier
304GTH6RNH
Background

Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.

Indication

Etonogestrel is administered in subdermal implants as long-acting reversible contraception. It is known to be effective in postpartum insertion including breastfeeding women.

Etonogestrel is part of the long-acting contraceptive implants that prevent pregnancy. The implant's effect can remain for 5 years.

Associated Conditions
-
Associated Therapies
Contraception, Contraceptive implant therapy

Etonogestrel Implants Protect Ovarian Reserve Function in Systemic Lupus Erythematosus

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-03-30
Last Posted Date
2023-03-30
Lead Sponsor
Sixth Affiliated Hospital, Sun Yat-sen University
Target Recruit Count
180
Registration Number
NCT05791799

Breastfeeding Etonogestrel Implant Study

Phase 4
Completed
Conditions
Interventions
First Posted Date
2019-06-07
Last Posted Date
2024-10-26
Lead Sponsor
University of New Mexico
Target Recruit Count
150
Registration Number
NCT03978598
Locations
🇺🇸

University of Utah, Salt Lake City, Utah, United States

🇺🇸

University of New Mexico, Albuquerque, New Mexico, United States

Abnormal Uterine Bleeding and Progestin-only Contraceptives

First Posted Date
2018-01-12
Last Posted Date
2020-12-17
Lead Sponsor
Assiut University
Target Recruit Count
390
Registration Number
NCT03398811
Locations
🇪🇬

Women Health Hospital - Assiut university, Assiut, Egypt

Clinical Trial the Use of Levonorgestrel-releasing Intrauterine System Versus Etonogestrel Implant in Endometriosis

Phase 4
Completed
Conditions
Interventions
First Posted Date
2015-06-24
Last Posted Date
2017-08-14
Lead Sponsor
University of Campinas, Brazil
Target Recruit Count
100
Registration Number
NCT02480647
Locations
🇧🇷

Nelsilene Mota Carvalho, Campinas, São Paulo, Brazil

A Pharmacokinetic Evaluation of Etonogestrel (ENG) Implant and Antiretroviral Therapy

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-03-10
Last Posted Date
2017-09-14
Lead Sponsor
University of Pittsburgh
Target Recruit Count
60
Registration Number
NCT02082652
Locations
🇺🇬

Infectious Disease Institute, Kampala, Uganda

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