Etonogestrel
- Generic Name
- Etonogestrel
- Brand Names
- Eluryng, Enilloring, Implanon, Nexplanon, Nuvaring
- Drug Type
- Small Molecule
- Chemical Formula
- C22H28O2
- CAS Number
- 54048-10-1
- Unique Ingredient Identifier
- 304GTH6RNH
- Background
Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.
- Indication
Etonogestrel is administered in subdermal implants as long-acting reversible contraception. It is known to be effective in postpartum insertion including breastfeeding women.
Etonogestrel is part of the long-acting contraceptive implants that prevent pregnancy. The implant's effect can remain for 5 years.
- Associated Therapies
- Contraception, Contraceptive implant therapy
Immediate vs. Delayed Postpartum Etonogestrel Implant
- Conditions
- Continuation Rate of Contraceptive Implant
- Interventions
- First Posted Date
- 2013-01-14
- Last Posted Date
- 2017-02-28
- Lead Sponsor
- Duke University
- Target Recruit Count
- 60
- Registration Number
- NCT01767285
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)
- Conditions
- Contraception
- Interventions
- First Posted Date
- 2012-10-18
- Last Posted Date
- 2024-05-28
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 666
- Registration Number
- NCT01709318
A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342B-057)
- Conditions
- Dysmenorrhea
- Interventions
- First Posted Date
- 2012-08-22
- Last Posted Date
- 2024-05-28
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 439
- Registration Number
- NCT01670656
Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers
- Conditions
- Vaginosis, Bacterial
- Interventions
- First Posted Date
- 2011-10-07
- Last Posted Date
- 2012-04-24
- Lead Sponsor
- Eastern Virginia Medical School
- Target Recruit Count
- 30
- Registration Number
- NCT01448291
- Locations
- 🇺🇸
Clinical Research Center at Eastern Virginia Medical School, Norfolk, Virginia, United States
Is Cerazette Use Before Nexplanon Insertion Predictive for Bleeding Pattern?
- Conditions
- Bleeding
- Interventions
- First Posted Date
- 2011-09-22
- Last Posted Date
- 2011-09-22
- Lead Sponsor
- VL-Medi Oy
- Target Recruit Count
- 90
- Registration Number
- NCT01438736
- Locations
- 🇫🇮
VL Medi Oy, Helsinki, Finland
Same-day Long-acting Reversible Contraception for Medication Abortion
- First Posted Date
- 2011-05-20
- Last Posted Date
- 2017-04-07
- Lead Sponsor
- Boston University
- Target Recruit Count
- 40
- Registration Number
- NCT01356927
- Locations
- 🇺🇸
Boston University Medical Center, Boston, Massachusetts, United States
Long-Acting Reversible Contraception
- Conditions
- Contraception
- Interventions
- First Posted Date
- 2011-02-18
- Last Posted Date
- 2018-02-28
- Lead Sponsor
- FHI 360
- Target Recruit Count
- 916
- Registration Number
- NCT01299116
- Locations
- 🇺🇸
Planned Parenthood Central North Carolina, Chapel Hill, North Carolina, United States
Acceptability of Long-term Progestin-only Contraception in Europe
- Conditions
- Contraception
- Interventions
- First Posted Date
- 2009-07-02
- Last Posted Date
- 2013-12-24
- Lead Sponsor
- Bayer
- Target Recruit Count
- 436
- Registration Number
- NCT00931827
Early Versus Standard Postpartum Insertion of the Etonogestrel Contraceptive Implant
- Conditions
- Complications; ContraceptiveFemale Lactation
- Interventions
- First Posted Date
- 2009-02-19
- Last Posted Date
- 2016-04-18
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 69
- Registration Number
- NCT00847587
- Locations
- 🇺🇸
University of Utah Hospital, Salt Lake City, Utah, United States
Safety of the Etonogestrel-releasing Implant During the Puerperium of Healthy Women
- Conditions
- BreastfeedingContraception
- Interventions
- First Posted Date
- 2009-01-26
- Last Posted Date
- 2017-05-15
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 40
- Registration Number
- NCT00828542
- Locations
- 🇧🇷
University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
Drug Development Updates
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