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Sofosbuvir and velpatasvir

Generic Name
Sofosbuvir and velpatasvir
Indication

1.用于治疗基因1~6型、混合型及未知型慢性丙型肝炎病毒(HCV) 的成人感染患者。

2.美国FDA批准用于治疗6岁及以上或体重超过17千克的6种基因型(GT-1,-2,-3,-4,-5,-6)的HCV儿童感染者(无肝硬化或轻度肝硬化)。

Generic VEL/SOF With or Without RBV for HIV/HCV Coinfected Patients

Phase 4
Completed
Conditions
Human Immunodeficiency Virus
Hepatitis C Virus Infection, Response to Therapy of
Interventions
First Posted Date
2017-08-16
Last Posted Date
2017-12-08
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
228
Registration Number
NCT03250910
Locations
🇨🇳

National Taiwan University Hospital, Yun-Lin Branch, Douliu, Taiwan

🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Opiate Dependence
Hepatitis C
Interventions
First Posted Date
2017-08-01
Last Posted Date
2021-05-13
Lead Sponsor
Community Research Initiative of New England
Target Recruit Count
11
Registration Number
NCT03235154
Locations
🇺🇸

Cambridge Health Alliance Outpatient Addiction Services, Somerville, Massachusetts, United States

Expanding the Pool in Orthotopic Heart Transplantation

Phase 2
Active, not recruiting
Conditions
Heart Transplant
Hepatitis C
Cardiac Transplant
Interventions
First Posted Date
2017-07-19
Last Posted Date
2025-02-04
Lead Sponsor
Mary E. Keebler, MD
Target Recruit Count
20
Registration Number
NCT03222531
Locations
🇺🇸

UPMC, Pittsburgh, Pennsylvania, United States

Lung Transplantation in Chronic HCV Infection With Post Transplant EPCLUSA Treatment

Phase 4
Terminated
Conditions
Hepatitis C, Chronic
Lung Transplant
Interventions
First Posted Date
2017-07-02
Last Posted Date
2019-09-11
Lead Sponsor
Duke University
Target Recruit Count
1
Registration Number
NCT03207399
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Transplanting Hepatitis C Positive Organs

Phase 4
Recruiting
Conditions
Hepatitis C
Awaiting Organ Transplant
Interventions
First Posted Date
2017-03-22
Last Posted Date
2022-10-12
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
148
Registration Number
NCT03086044
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Sofosbuvir/Velpatasvir in Postpartum Women With Opioid Use Disorder and Chronic Hepatitis C Infection

Phase 4
Completed
Conditions
Opioid-use Disorder
Hepatitis C, Chronic
Interventions
First Posted Date
2017-02-20
Last Posted Date
2023-05-06
Lead Sponsor
Elizabeth Krans, MD
Target Recruit Count
32
Registration Number
NCT03057847
Locations
🇺🇸

Magee Womens Hospital of UPMC, Pittsburgh, Pennsylvania, United States

Sofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open Label Trial

Phase 4
Completed
Conditions
Thalassemia
Hepatitis C
Interventions
First Posted Date
2017-01-26
Last Posted Date
2018-10-11
Lead Sponsor
Ala'a Sharara
Target Recruit Count
7
Registration Number
NCT03032666
Locations
🇱🇧

American University of Beirut Medical Center, Beirut, Lebanon

Efficacy of All-Oral Anti-Viral Therapy for Symptomatic Hepatitis C Virus Infection-Related Cryoglobulinemia

Phase 2
Completed
Conditions
Hepatitis C
Cryoglobulinemia
Interventions
First Posted Date
2016-07-07
Last Posted Date
2020-12-17
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
10
Registration Number
NCT02825212
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

Surveillance and Treatment of Prisoners With Hepatitis C

Phase 4
Completed
Conditions
Hepatitis C
Interventions
First Posted Date
2014-02-17
Last Posted Date
2019-12-09
Lead Sponsor
Kirby Institute
Target Recruit Count
3692
Registration Number
NCT02064049
Locations
🇦🇺

Goulburn Correctional Centre, Goulburn, New South Wales, Australia

🇦🇺

Dillwynia Correctional Centre, Windsor, New South Wales, Australia

🇦🇺

Outer Metropolitan Multipurpose Correctional Centre, Windsor, New South Wales, Australia

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