Prednisone
- Generic Name
- Prednisone
- Brand Names
- Deltasone, Rayos, Winpred
- Drug Type
- Small Molecule
- Chemical Formula
- C21H26O5
- CAS Number
- 53-03-2
- Unique Ingredient Identifier
- VB0R961HZT
- Background
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.
Prednisone was granted FDA approval on 21 February 1955.
- Indication
Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.
- Associated Conditions
- Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
Drug Therapy in Lupus Nephropathy
- Conditions
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2008-04-09
- Target Recruit Count
- 45
- Registration Number
- NCT00001212
- Locations
- 🇺🇸
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, Maryland, United States
Serologically Active, Clinically Stable Systemic Lupus Erythematosus
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2016-03-04
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 154
- Registration Number
- NCT00000421
- Locations
- 🇺🇸
Office of Betty Diamond, M.D., Bronx, New York, United States
🇺🇸North Shore-Long Island Jewish Health System, New Hyde Park, New York, United States
🇺🇸Lenox Hill Hospital, New York, New York, United States
Multicenter Trial of Prednisone in Alzheimer's Disease
- Conditions
- First Posted Date
- 1999-11-01
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Institute on Aging (NIA)
- Registration Number
- NCT00000178
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
🇺🇸University of Southern California, Los Angeles, California, United States
🇺🇸Johns Hopkins University, Baltimore, Maryland, United States
Diffuse Fibrotic Lung Disease
- Conditions
Myocarditis Treatment Trial
- Conditions
- First Posted Date
- 1999-10-28
- Last Posted Date
- 2023-04-18
- Lead Sponsor
- University of Utah
- Registration Number
- NCT00000524
Phase II Randomized Study of Muromonab-CD3, Cyclosporine, Methylprednisolone, and Prednisone in Patients With Giant Cell Myocarditis
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2010-09-09
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 40
- Registration Number
- NCT00004482
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Randomized Study of Hormonal Regulation of Infantile Hemangioma
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2015-03-25
- Lead Sponsor
- FDA Office of Orphan Products Development
- Target Recruit Count
- 30
- Registration Number
- NCT00004436
Alternate Day Prednisone or Daily Fish Oil Supplements in Patients With Immunoglobulin A Nephropathy
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2008-09-10
- Target Recruit Count
- 123
- Registration Number
- NCT00004448
Optic Neuritis Treatment Trial (ONTT)
- Conditions
- First Posted Date
- 1999-09-24
- Last Posted Date
- 2006-06-05
- Lead Sponsor
- National Eye Institute (NEI)
- Registration Number
- NCT00000146
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸Baylor College of Medicine, Houston, Texas, United States
🇺🇸California Pacific Medical Center, San Francisco, California, United States
Longitudinal Optic Neuritis Study (LONS)
- Conditions
- First Posted Date
- 1999-09-24
- Last Posted Date
- 2006-05-29
- Lead Sponsor
- National Eye Institute (NEI)
- Registration Number
- NCT00000147
- Locations
- 🇺🇸
University of Florida, Gainesville, Florida, United States
🇺🇸Swedish Medical Center, Seattle, Washington, United States
🇺🇸University of Arkansas, Little Rock, Arkansas, United States
Drug Development Updates
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