Prednisone
- Generic Name
- Prednisone
- Brand Names
- Deltasone, Rayos, Winpred
- Drug Type
- Small Molecule
- Chemical Formula
- C21H26O5
- CAS Number
- 53-03-2
- Unique Ingredient Identifier
- VB0R961HZT
- Background
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.
Prednisone was granted FDA approval on 21 February 1955.
- Indication
Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.
- Associated Conditions
- Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
A Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously Untreated Advanced Diffuse Large B-Cell Lymphoma (GATHER)
- Conditions
- Lymphoma, B-Cell
- Interventions
- First Posted Date
- 2011-08-11
- Last Posted Date
- 2018-04-25
- Lead Sponsor
- Genentech, Inc.
- Target Recruit Count
- 100
- Registration Number
- NCT01414855
- Locations
- 🇺🇸
Norwalk Hospital, Norwalk, Connecticut, United States
🇺🇸Onc Hem Assoc of Central IL, Peoria, Illinois, United States
🇺🇸Florida Cancer Specialists; Saint Petersburg, Saint Petersburg, Florida, United States
Oral Prednisone Taper Versus Placebo for the Treatment of Acute Relapses in Multiple Sclerosis
- First Posted Date
- 2011-08-08
- Last Posted Date
- 2015-12-18
- Lead Sponsor
- Claudio Gobbi
- Target Recruit Count
- 27
- Registration Number
- NCT01411514
- Locations
- 🇨🇭
Osepdale Civico, Lugano, Ticino, Switzerland
Male Infertility Related With Post Infection Inflammatory Syndrome
- Conditions
- LeukopeniaMale InfertilityPostinfection InflammationOxidative Stress
- Interventions
- Drug: PlaceboDrug: Prednisone
- First Posted Date
- 2011-08-02
- Last Posted Date
- 2018-03-19
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 200
- Registration Number
- NCT01407484
- Locations
- 🇫🇷
Cochin Hospital, Paris, France
Steroids and Azathioprine in Advanced IgAN
- Conditions
- IgA NephropathyChronic Kidney Disease
- Interventions
- First Posted Date
- 2011-07-13
- Last Posted Date
- 2011-07-13
- Lead Sponsor
- A. Manzoni Hospital
- Target Recruit Count
- 46
- Registration Number
- NCT01392833
Study Comparing Doses Of An Experimental Glucocorticoid Compound To Prednisone And Placebo In Rheumatoid Arthritis
- Conditions
- Rheumatoid Arthritis
- Interventions
- First Posted Date
- 2011-07-13
- Last Posted Date
- 2018-12-14
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 323
- Registration Number
- NCT01393639
- Locations
- 🇧🇬
Revmatologichno Otdelenie, MBAL - Plovdiv, Plovdiv, Bulgaria
🇧🇬MBAL "Sveti Ivan Rilski" Sofia; Klinika po Revmatologia, Sofia, Bulgaria
🇲🇽Centro de Estudios de Investigacion Basica y Clinica SC., Guadalajara, Jalisco, Mexico
Abiraterone Acetate Combined With Dutasteride for Metastatic Castrate Resistant Prostate Cancer
- Conditions
- Prostate Cancer
- Interventions
- First Posted Date
- 2011-07-13
- Last Posted Date
- 2018-03-15
- Lead Sponsor
- Mary-Ellen Taplin, MD
- Target Recruit Count
- 40
- Registration Number
- NCT01393730
- Locations
- 🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸Seattle Cancer Care Alliance, Seattle, Washington, United States
🇺🇸University of Washington Medical Center, Seattle, Washington, United States
Chemotherapy Based on PET Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma
- Conditions
- Lymphoma
- Interventions
- First Posted Date
- 2011-07-11
- Last Posted Date
- 2023-06-29
- Lead Sponsor
- ECOG-ACRIN Cancer Research Group
- Target Recruit Count
- 6
- Registration Number
- NCT01390584
- Locations
- 🇺🇸
Stanford Cancer Center, Stanford, California, United States
🇺🇸McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center, Reading, Pennsylvania, United States
Pazopanib, Docetaxel, Prednisone Prostate
- Conditions
- Prostate Cancer
- Interventions
- First Posted Date
- 2011-06-30
- Last Posted Date
- 2018-06-06
- Lead Sponsor
- Daniel George, MD
- Target Recruit Count
- 36
- Registration Number
- NCT01385228
- Locations
- 🇺🇸
Duke Cancer Institute, Durham, North Carolina, United States
🇺🇸The University of Chicago, Chicago, Illinois, United States
Study of Lenalidomide and Docetaxel in Subjects With Androgen Independent Prostate Cancer
- Conditions
- Prostate Cancer
- Interventions
- First Posted Date
- 2011-06-22
- Last Posted Date
- 2016-05-09
- Lead Sponsor
- Columbia University
- Target Recruit Count
- 64
- Registration Number
- NCT01378091
- Locations
- 🇺🇸
Cornell Weill Medical Center, New York, New York, United States
🇺🇸Columbia University Medical Center, New York, New York, United States
Bendamustine, Bortezomib (Velcade ®) and Prednisone (BVP) in Patients Newly Diagnosed Multiple Myeloma
- Conditions
- Multiple Myeloma
- First Posted Date
- 2011-06-20
- Last Posted Date
- 2016-05-17
- Lead Sponsor
- PETHEMA Foundation
- Target Recruit Count
- 60
- Registration Number
- NCT01376401
- Locations
- 🇪🇸
Hospital Universitario La Fe, Valencia, Spain
🇪🇸Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain
🇪🇸Hospital Clínic, Barcelona, Spain
Drug Development Updates
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