Prednisone

Generic Name: Prednisone

Brand Names: Deltasone, Rayos, Winpred

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₆O_₅

CAS Number: 53-03-2

Unique Ingredient Identifier: VB0R961HZT

Background: A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.

Prednisone was granted FDA approval on 21 February 1955.

Indication: Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.

Associated Conditions: Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis

Associated Therapies: Palliative Treatment

Clinical Trials

Combination Chemotherapy and Rituximab With Pegfilgrastim Followed by Rituximab, in Large B-Cell Non-Hodgkin's Lymphoma

Phase 2

Completed

Conditions: Non-Hodgkins Lymphoma

Interventions: Drug: Cyclophosphamide
Drug: Mitoxantrone
Drug: Vincristine
Drug: Prednisone
Drug: Rituximab

First Posted Date: 2005-09-19

Last Posted Date: 2022-03-03

Lead Sponsor: SCRI Development Innovations, LLC

Target Recruit Count: 51

Registration Number: NCT00193479

Locations: 🇺🇸
Tennessee Oncology, Nashville, Tennessee, United States
🇺🇸
Florida Cancer Specialists, Fort Myers, Florida, United States

A Trial of Antenatal Treatment of Alloimmune Thrombocytopenia

Phase 2

Completed

Conditions: Alloimmune Thrombocytopenia
Fetal Alloimmune Thrombocytopenia

Interventions: Drug: IVIG (Intravenous Immunoglobulin)
Drug: prednisone

First Posted Date: 2005-09-19

Last Posted Date: 2018-11-07

Lead Sponsor: Weill Medical College of Cornell University

Target Recruit Count: 102

Registration Number: NCT00194987

Locations: 🇺🇸
New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York, United States

Calcitriol, Mitoxantrone, and Prednisone in Treating Patients With Metastatic Prostate Cancer

Phase 2

Completed

Conditions: Prostate Cancer

First Posted Date: 2005-09-16

Last Posted Date: 2017-05-03

Lead Sponsor: OHSU Knight Cancer Institute

Target Recruit Count: 19

Registration Number: NCT00182741

Locations: 🇺🇸
Cancer Institute at Oregon Health and Science University, Portland, Oregon, United States

Treatment for Patients With Stage III or IV Non-Hodgkin Lymphoma

Not Applicable

Completed

Conditions: Lymphoblastic Lymphoma

Interventions: Drug: Vincristine
Procedure: Radiation Therapy
Drug: Daunomycin
Drug: L-Asparaginase
Drug: Cytarabine
Drug: Methotrexate
Drug: Mercaptopurine
Drug: Etoposide
Drug: Cyclophosphamide
Drug: Prednisone
Drug: Dexamethasone

First Posted Date: 2005-09-16

Last Posted Date: 2008-04-23

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 42

Registration Number: NCT00187122

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Efficacy Studies of Corticosteroid Therapy in Community-Acquired Pneumonia

Phase 3

Completed

Conditions: Pneumonia

First Posted Date: 2005-09-15

Last Posted Date: 2008-09-29

Lead Sponsor: Medical Center Alkmaar

Target Recruit Count: 216

Registration Number: NCT00170196

Locations: 🇳🇱
Medisch Centrum Alkmaar, Alkmaar, Noord-Holland, Netherlands

A Phase II Study of Rituximab Combined With CHOP in T-cell Angio-immunoblastic Lymphoma

Phase 2

Completed

Conditions: Untreated T-cell Angioimmunoblastic Lymphoma

Interventions: Drug: Rituximab
Drug: Prednisone
Drug: Doxorubicine
Drug: Cyclophosphamide
Drug: Vincristine

First Posted Date: 2005-09-15

Last Posted Date: 2017-03-13

Lead Sponsor: Lymphoma Study Association

Target Recruit Count: 27

Registration Number: NCT00169156

Locations: 🇫🇷
Hôpital Henri Mondor, Créteil, France
🇫🇷
Service d'Hématologie - Centre Hospitalier Lyon-Sud, Pierre-Bénite cedex, France
🇫🇷
Centre Henri Becquerel, Rouen, France

and more 1 locations