MedPath

Ethambutol

Generic Name
Ethambutol
Brand Names
Etibi, Myambutol
Drug Type
Small Molecule
Chemical Formula
C10H24N2O2
CAS Number
74-55-5
Unique Ingredient Identifier
8G167061QZ

Overview

Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA approval on 6 November 1967.

Background

Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA approval on 6 November 1967.

Indication

Ethambutol is indicated in combination with other anti-tuberculosis drugs in the treatment of pulmonary tuberculosis. Ethambutol is commonly used in combination with isoniazid, rifampin, and pyrazinamide.

Associated Conditions

  • Mycobacterium Avium Intracellulare Complex (MAC)
  • Mycobacterium Infections
  • Pulmonary Tuberculosis (TB)

Clinical Trials

Phase 2
Not yet recruiting
Posted: 2025/04/08
Sponsor:
Shandong University
Phase 3
Not yet recruiting
Posted: 2025/04/01
Sponsor:
Shenzhen Third Peopl...

FDA Approved Products

Ethambutol Hydrochloride
Manufacturer:STI Pharma
Route:ORAL
Strength:400 mg in 1 1
Approved: 2011/01/31
NDC:68850-005
Ethambutol Hydrochloride
Manufacturer:STI Pharma
Route:ORAL
Strength:100 mg in 1 1
Approved: 2011/01/31
NDC:68850-004
Ethambutol Hydrochloride
Manufacturer:STI Pharma LLC
Route:ORAL
Strength:100 mg in 1 1
Approved: 2024/01/12
NDC:54879-001
ETHAMBUTOL HYDROCHLORIDE
Manufacturer:Epic Pharma, LLC
Route:ORAL
Strength:400 mg in 1 1
Approved: 2020/07/30
NDC:42806-102
Ethambutol Hydrochloride
Manufacturer:STI Pharma LLC
Route:ORAL
Strength:400 mg in 1 1
Approved: 2024/01/12
NDC:54879-002

Singapore Approved Products

EBUTOL-100 TABLET 100 mg
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:TABLET, FILM COATED
Strength:100 mg
Online:Yes
Approved: 1989/06/05
Approval:SIN03004P
EBUTOL-400 TABLET 400 mg
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:TABLET, FILM COATED
Strength:400 mg
Online:Yes
Approved: 1989/06/05
Approval:SIN03005P

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