D-Glutamine
- Generic Name
- D-Glutamine
- Brand Names
- Endari
- Drug Type
- Small Molecule
- Chemical Formula
- C5H10N2O3
- CAS Number
- 5959-95-5
- Unique Ingredient Identifier
- 63HB36CA2Y
- Background
A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells.
- Indication
Used for nutritional supplementation, also for treating dietary shortage or imbalance.
Used to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older .
- Associated Conditions
- Osteoporosis, Acute Complications of Sickle Cell Disease
- Associated Therapies
- -
Effect of Oral Glutamine on Muscle Mass and Function in Duchenne Muscular Dystrophy
- First Posted Date
- 2006-02-27
- Last Posted Date
- 2007-12-21
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 30
- Registration Number
- NCT00296621
- Locations
- 🇫🇷
Service d'Hépato Gastro Entérologie, Hôpital Jeanne de Flandre, CHR&U de Lille, Lille, France
🇫🇷Service de Neuropédiatrie, Hôpital Roger Salengro, CHR&U de Lille, Lille, France
🇫🇷Pédiatrie Multidisciplinaire et Nutrition de l'Enfant, Centre Hospitalier Universitaire de Poitiers, Poitiers, France
Study of Glutamine as Prophylaxis for Irinotecan Induced Diarrhea
- First Posted Date
- 2005-11-18
- Last Posted Date
- 2016-02-25
- Lead Sponsor
- AHS Cancer Control Alberta
- Target Recruit Count
- 130
- Registration Number
- NCT00255229
- Locations
- 🇨🇦
Cross Cancer Institute, Edmonton, Alberta, Canada
Glutamine and Intestinal Protein Metabolism
- Conditions
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2013-06-18
- Lead Sponsor
- University Hospital, Rouen
- Target Recruit Count
- 30
- Registration Number
- NCT00213551
- Locations
- 🇫🇷
University Hospital of Rouen, Rouen, France
Randomized Placebo-Controlled Trial of Glutamine for Breast Cancer Patients With Peripheral Neuropathy
- Conditions
- Interventions
- First Posted Date
- 2005-09-19
- Last Posted Date
- 2018-06-06
- Lead Sponsor
- Weill Medical College of Cornell University
- Target Recruit Count
- 30
- Registration Number
- NCT00195013
- Locations
- 🇺🇸
Weill Medical College of Cornell University, New York, New York, United States
Enteral Glutamine Supplementation for the Patient With Major Torso Trauma
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2010-04-23
- Target Recruit Count
- 20
- Registration Number
- NCT00178581
- Locations
- 🇺🇸
University of Texas Health Science Center at Houston, Houston, Texas, United States
Long-term Impact and Intervention for Diarrhea in Brazil
- Conditions
- Interventions
- First Posted Date
- 2005-08-23
- Last Posted Date
- 2011-03-08
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 321
- Registration Number
- NCT00133406
- Locations
- 🇧🇷
Federal University of Ceará, Fortaleza, Brazil
Trial of Oral Glutamine in Patients With Sickle Cell Anemia
- First Posted Date
- 2005-08-18
- Last Posted Date
- 2017-04-26
- Lead Sponsor
- St. Jude Children's Research Hospital
- Target Recruit Count
- 27
- Registration Number
- NCT00131508
- Locations
- 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia
- First Posted Date
- 2005-08-02
- Last Posted Date
- 2021-01-29
- Lead Sponsor
- Emmaus Medical, Inc.
- Target Recruit Count
- 70
- Registration Number
- NCT00125788
- Locations
- 🇺🇸
Kaiser Permanente, Bellflower, California, United States
🇺🇸Harbor-UCLA Medical Center, Torrance, California, United States
🇺🇸Jacobi Medical Center, Bronx, New York, United States
A Multicenter Randomized Placebo-Controlled Double-Blind Study to Assess Efficacy and Safety of Glutamine and Creatine Monohydrate in Duchenne Muscular Dystrophy (DMD)
- Conditions
- First Posted Date
- 2001-07-05
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Registration Number
- NCT00018109
- Locations
- 🇺🇸
Washington University School of Medicine, St. Louis, Missouri, United States
Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy
- Conditions
- First Posted Date
- 2001-05-23
- Last Posted Date
- 2011-10-27
- Target Recruit Count
- 48
- Registration Number
- NCT00016653
- Locations
- 🇺🇸
Children's National Medical Center, Washington, District of Columbia, United States
Drug Development Updates
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