Pentobarbital
- Generic Name
- Pentobarbital
- Brand Names
- Nembutal
- Drug Type
- Small Molecule
- Chemical Formula
- C11H18N2O3
- CAS Number
- 76-74-4
- Unique Ingredient Identifier
- I4744080IR
- Background
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
- Indication
For the short-term treatment of insomnia.
- Associated Conditions
- Convulsions, Insomnia
- Associated Therapies
- Anesthetic premedication therapy, Emergency Care
A Comparison of Two Sedation Techniques in Children Undergoing Transthoracic Echocardiography (TTE)
- Conditions
- Heart Disease
- Interventions
- First Posted Date
- 2014-09-26
- Last Posted Date
- 2020-01-21
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Target Recruit Count
- 280
- Registration Number
- NCT02250820
- Locations
- 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
Dexmedetomidine Versus Pentobarbital for Pediatric Procedural Sedation
- Conditions
- Sedation
- Interventions
- First Posted Date
- 2009-04-08
- Last Posted Date
- 2018-06-28
- Lead Sponsor
- Washington University School of Medicine
- Registration Number
- NCT00878345
- Locations
- 🇺🇸
St. Louis Children's Hospital, Saint Louis, Missouri, United States
Comparison of Effectiveness of Pentobarbital and Thiopental in Patients With Refractory Intracranial Hypertension
- First Posted Date
- 2008-02-25
- Last Posted Date
- 2008-02-25
- Lead Sponsor
- Hospital Universitari Son Dureta
- Target Recruit Count
- 44
- Registration Number
- NCT00622570
- Locations
- 🇪🇸
Son Dureta Hospital, Palma, Balearic Island, Spain
GHB Withdrawal Symptoms and Effectiveness of Treatment With Lorazepam Versus Pentobarbital - 1
- Conditions
- Substance-Related Disorders
- Interventions
- First Posted Date
- 2005-07-25
- Last Posted Date
- 2016-05-12
- Lead Sponsor
- University of California, Los Angeles
- Registration Number
- NCT00123578
- Locations
- 🇺🇸
UCLA, Los Angeles, California, United States
Physiological, Behavioral and Subjective Effects of Drugs (GHB)
- Conditions
- Sedative Abuse
- Interventions
- First Posted Date
- 2003-04-16
- Last Posted Date
- 2008-09-10
- Lead Sponsor
- Orphan Medical
- Target Recruit Count
- 20
- Registration Number
- NCT00058955
- Locations
- 🇺🇸
Johns Hopkins University School of Medicine/Bayview Medical Center, Baltimore, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.