Abciximab
- Generic Name
- Abciximab
- Brand Names
- -
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 143653-53-6
- Unique Ingredient Identifier
- X85G7936GV
- Background
Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets and vess...
- Indication
Abciximab is indicated as an adjunct to percutaneous coronary intervention for the prevention of cardiac ischemic complications in patients undergoing percutaneous coronary intervention and in patients with unstable angina not responding to conventional medical therapy when percutaneous coronary intervention is planned within 24 hours. Abciximab is intended ...
- Associated Conditions
- Ischemic cardiovascular events
- Associated Therapies
- -
Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in Patients With Acute Myocardial Infarction (AMI)
- Conditions
- Interventions
- First Posted Date
- 2014-07-08
- Last Posted Date
- 2014-07-14
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 5989
- Registration Number
- NCT02181985
A Randomized Trial of Intracoronary Reopro to Improve Coronary Microvascular Function
- First Posted Date
- 2014-04-07
- Last Posted Date
- 2014-04-07
- Lead Sponsor
- University of Melbourne
- Target Recruit Count
- 40
- Registration Number
- NCT02105870
- Locations
- 🇦🇺
St Vincent's Hospital, Fitzroy, Victoria, Australia
Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis
- Conditions
- Interventions
- First Posted Date
- 2013-08-30
- Last Posted Date
- 2015-03-26
- Lead Sponsor
- St. Louis University
- Registration Number
- NCT01932554
- Locations
- 🇺🇸
Cardinal Glennon Children's Medical Center, St. Louis, Missouri, United States
Randomized Trial of Standard vs ClearWay-infused Abciximab and Thrombectomy for Myocardial Infarction
- Conditions
- Interventions
- First Posted Date
- 2011-12-26
- Last Posted Date
- 2012-01-05
- Lead Sponsor
- CLI Foundation
- Target Recruit Count
- 128
- Registration Number
- NCT01499407
- Locations
- 🇮🇹
A. O. S. Giovanni Addolorata, Rome, RM, Italy
Tailored Antiplatelet Therapy During Percutaneous Coronary Intervention in Patients With Diabetes Mellitus
- First Posted Date
- 2011-11-21
- Last Posted Date
- 2012-12-13
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 130
- Registration Number
- NCT01475552
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam, Korea, Republic of
Comparison of Drug Eluting and Bare Metal Stents With or Without Abciximab in ST Elevation Myocardial Infarction
- First Posted Date
- 2009-09-29
- Last Posted Date
- 2011-07-26
- Lead Sponsor
- Catharina Ziekenhuis Eindhoven
- Target Recruit Count
- 907
- Registration Number
- NCT00986050
- Locations
- 🇳🇱
Catharina ziekenhuis, Eindhoven, Brabant, Netherlands
Comparison of Intracoronary Versus Intravenous Abciximab in ST-segment Elevation Myocardial Infarction (CICERO)
- First Posted Date
- 2009-06-25
- Last Posted Date
- 2010-09-08
- Lead Sponsor
- University Medical Center Groningen
- Target Recruit Count
- 534
- Registration Number
- NCT00927615
- Locations
- 🇳🇱
University Medical Centre Groningen, Groningen, Netherlands
Intravenous Versus Intracoronary Use of Abciximab
- First Posted Date
- 2008-05-28
- Last Posted Date
- 2011-08-10
- Lead Sponsor
- University Hospital, Gentofte, Copenhagen
- Target Recruit Count
- 355
- Registration Number
- NCT00685464
- Locations
- 🇩🇰
Dept. of Cardiology, Gentofte University Hospital, Hellerup, Denmark
Myocardial Infarction With ST-Elevation
- First Posted Date
- 2008-03-19
- Last Posted Date
- 2009-09-17
- Lead Sponsor
- University Hospital, Strasbourg, France
- Target Recruit Count
- 292
- Registration Number
- NCT00638638
- Locations
- 🇫🇷
Service de Cardiologie - Hôpital de Hautepierre - 1, Avenue Molière, Strasbourg, France
A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI and Rescue-PCI
- First Posted Date
- 2007-02-27
- Last Posted Date
- 2013-05-08
- Lead Sponsor
- Olivier F. Bertrand
- Target Recruit Count
- 74
- Registration Number
- NCT00440895
- Locations
- 🇨🇦
Laval Hospital, Quebec, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.