Muromonab

Generic Name
Muromonab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
140608-64-6
Unique Ingredient Identifier
JGA39ICE2V
Background

Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a).

Indication

For treatment of organ transplant recipients, prevention of organ rejection

Associated Conditions
Acute Renal Allograft Rejection, Steroid resistant Heart transplant rejection, Steroid resistant hepatic transplant rejection
Associated Therapies
-
Clinical Trials
Related News

Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

First Posted Date
2007-12-03
Last Posted Date
2020-04-14
Lead Sponsor
St. Jude Children's Research Hospital
Target Recruit Count
73
Registration Number
NCT00566696
Locations
🇺🇸

St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Study of Muromonab-CD3 and Cyclosporine in Patients With Giant Cell Myocarditis

Not Applicable
Completed
Conditions
Myocarditis
First Posted Date
2001-12-07
Last Posted Date
2015-03-25
Lead Sponsor
Mayo Clinic
Target Recruit Count
40
Registration Number
NCT00027443
Locations
🇺🇸

Mayo Clinic Rochester, Rochester, Minnesota, United States

Phase II Randomized Study of Muromonab-CD3, Cyclosporine, Methylprednisolone, and Prednisone in Patients With Giant Cell Myocarditis

Phase 2
Completed
Conditions
Myocarditis
Giant Cell Myocarditis
First Posted Date
1999-10-19
Last Posted Date
2010-09-09
Lead Sponsor
Mayo Clinic
Target Recruit Count
40
Registration Number
NCT00004482
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy