Desipramine
- Generic Name
- Desipramine
- Brand Names
- Norpramin
- Drug Type
- Small Molecule
- Chemical Formula
- C18H22N2
- CAS Number
- 50-47-5
- Unique Ingredient Identifier
- TG537D343B
- Background
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipram...
- Indication
For relief of symptoms in various depressive syndromes, especially endogenous depression. It has also been used to manage chronic peripheral neuropathic pain, as a second line agent for the management of anxiety disorders (e.g. panic disorder, generalized anxiety disorder), and as a second or third line agent in the ADHD management.
- Associated Conditions
- Anorexia Nervosa (AN), Bulimia Nervosa, Chronic Pain, Depression, Diabetic Neuropathies, Insomnia, Irritable Bowel Syndrome (IBS), Neuropathic Pain, Panic Disorder, Postherpetic Neuralgia
- Associated Therapies
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