Acebutolol

Generic Name
Acebutolol
Brand Names
Sectral
Drug Type
Small Molecule
Chemical Formula
C18H28N2O4
CAS Number
37517-30-9
Unique Ingredient Identifier
67P356D8GH
Background

A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.

Indication

For the management of hypertension and ventricular premature beats in adults.

Associated Conditions
Chronic Stable Angina Pectoris, Hypertension, Ventricular Arrhythmia
Associated Therapies
-

Efficacy and Safety of Propranolol Versus Acebutolol on the Proliferative Phase of Infantile Hemangioma

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2012-12-06
Last Posted Date
2016-06-01
Lead Sponsor
University Hospital, Montpellier
Target Recruit Count
55
Registration Number
NCT01743885
Locations
🇫🇷

Chirurgy Plastic Department, Montpellier, France

🇫🇷

UH Lyon, Lyon, France

🇫🇷

UH NCaremeau, Nîmes, France

and more 1 locations

An Open-label, Single-dose, Two-treatment, Randomized, Cross-over Study to Investigate the Effects of the SLCO2B1 c.1457C>T Polymorphism and Apple Juice on the Pharmacokinetics and Pharmacodynamics of Acebutolol in Healthy Korean and Japanese Volunteers

Phase 4
Completed
Conditions
Interventions
First Posted Date
2012-01-20
Last Posted Date
2012-06-20
Lead Sponsor
In-Jin Jang, MD, PhD
Target Recruit Count
16
Registration Number
NCT01514019
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

🇯🇵

General Clinical Research Center, Oita University Hospital, Oita, Japan

Treatment of Mild Hypertension Study (TOMHS)

First Posted Date
1999-10-28
Last Posted Date
2016-02-25
Lead Sponsor
University of Minnesota
Registration Number
NCT00000522
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