gamma-Hydroxybutyric acid

Generic Name
gamma-Hydroxybutyric acid
Brand Names
Xywav
Drug Type
Small Molecule
Chemical Formula
C4H8O3
CAS Number
591-81-1
Unique Ingredient Identifier
30IW36W5B2
Background

Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug...

Indication

Used as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance.

Associated Conditions
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Associated Therapies
-

Stimulating Amyloid Clearance in Cerebral Amyloid Angiopathy

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-05-20
Last Posted Date
2024-05-20
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
60
Registration Number
NCT06421532

Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress Disorder

First Posted Date
2020-08-11
Last Posted Date
2022-10-04
Lead Sponsor
Psychiatric University Hospital, Zurich
Target Recruit Count
27
Registration Number
NCT04508166
Locations
🇨🇭

University of Zurich, Zürich, Select An Option…, Switzerland

Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and Cobicistat

First Posted Date
2020-03-26
Last Posted Date
2020-07-22
Lead Sponsor
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Target Recruit Count
12
Registration Number
NCT04322214
Locations
🇪🇸

José, Badalona, Barcelona, Spain

Memory Enhancement by Gamma-hydroxybutyrate vs. Trazodone in Major Depressive Disorder.

First Posted Date
2019-09-09
Last Posted Date
2022-05-12
Lead Sponsor
Erich Seifritz
Target Recruit Count
54
Registration Number
NCT04082806
Locations
🇨🇭

Psychiatric University Hospital, Zürich, ZH, Switzerland

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