Midomafetamine
- Generic Name
- Midomafetamine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C11H15NO2
- CAS Number
- 42542-10-9
- Unique Ingredient Identifier
- KE1SEN21RM
- Background
An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems.
- Indication
Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used illicit drugs in the U.S.
- Associated Conditions
- -
- Associated Therapies
- -
Evaluation of MDMA on Startle Response
- Conditions
- Interventions
- First Posted Date
- 2017-06-09
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Lykos Therapeutics
- Target Recruit Count
- 34
- Registration Number
- NCT03181763
- Locations
- 🇺🇸
Emory University, Atlanta, Georgia, United States
Effects of MDMA on Emotional and Social Memories
- First Posted Date
- 2017-02-13
- Last Posted Date
- 2018-06-29
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 84
- Registration Number
- NCT03050541
Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing
- Conditions
- Interventions
- First Posted Date
- 2017-01-13
- Last Posted Date
- 2018-10-15
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 28
- Registration Number
- NCT03019822
- Locations
- 🇨ðŸ‡
University Hospital Basel, Basel, Basel Stadt, Switzerland
MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD
- Conditions
- Interventions
- First Posted Date
- 2016-08-23
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Lykos Therapeutics
- Target Recruit Count
- 12
- Registration Number
- NCT02876172
- Locations
- 🇺🇸
Offices of Michael Mithoefer MD, Mount Pleasant, South Carolina, United States
Abuse Liability and Human Pharmacology of Mephedrone
- Conditions
- Interventions
- First Posted Date
- 2014-09-05
- Last Posted Date
- 2014-12-04
- Lead Sponsor
- Parc de Salut Mar
- Target Recruit Count
- 12
- Registration Number
- NCT02232789
- Locations
- 🇪🇸
Institut Hospital del Mar d'Investigacions Mèdiques-IMIM. Parc de Salut Mar., Barcelona, Spain
Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD
- Conditions
- Interventions
- First Posted Date
- 2014-04-03
- Last Posted Date
- 2024-11-05
- Lead Sponsor
- Lykos Therapeutics
- Target Recruit Count
- 10
- Registration Number
- NCT02102802
- Locations
- 🇺🇸
Offices of Michael Mithoefer, Mount Pleasant, South Carolina, United States
Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSD
- Conditions
- Interventions
- First Posted Date
- 2013-10-09
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Lykos Therapeutics
- Target Recruit Count
- 6
- Registration Number
- NCT01958593
- Locations
- 🇨🇦
Offices of Dr. Ingrid Pacey MBBS FRCP[C], Vancouver, British Columbia, Canada
Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study
- Conditions
- Interventions
- First Posted Date
- 2013-09-26
- Last Posted Date
- 2016-01-21
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 24
- Registration Number
- NCT01951508
- Locations
- 🇨ðŸ‡
University Hospital Basel, Basel, Basel-Stadt, Switzerland
Influence of Bupropion on the Effects of MDMA
- Conditions
- Interventions
- First Posted Date
- 2013-01-18
- Last Posted Date
- 2016-01-21
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 16
- Registration Number
- NCT01771874
- Locations
- 🇨ðŸ‡
University Hospital Basel, Basel, Basel-Stadt, Switzerland
Effects of MDMA and Methylphenidate on Social Cognition
- Conditions
- Interventions
- First Posted Date
- 2012-06-11
- Last Posted Date
- 2018-12-11
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 30
- Registration Number
- NCT01616407
- Locations
- 🇨ðŸ‡
University Hospital Basel, Basel, Switzerland
Drug Development Updates
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