Zinc

Generic Name: Zinc

Brand Names: Vitafol-one, Wilzin

Drug Type: Small Molecule

Chemical Formula: Zn

CAS Number: 7440-66-6

Unique Ingredient Identifier: J41CSQ7QDS

Background: A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is identified by the ...

Indication: Zinc can be used for the treatment and prevention of zinc deficiency/its consequences, including stunted growth and acute diarrhea in children, and slowed wound healing. It is also utilized for boosting the immune system, treating the common cold and recurrent ear infections, as well as preventing lower respiratory tract infections .

Associated Conditions: Candidiasis, Common Cold, Diaper Dermatitis, Diaper Rash, Eye redness, Iron Deficiency (ID), Ocular Irritation, Skin Irritation, Sunburn, Wilson's Disease, Zinc Deficiency

Associated Therapies: Dietary and Nutritional Therapies, Dietary supplementation

Clinical Trials

Immunological and Clinical Responses to Zinc in Children With Diarrhoea

Phase 3

Completed

Conditions: Diarrhoea

First Posted Date: 2006-12-06

Last Posted Date: 2009-02-20

Lead Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh

Target Recruit Count: 338

Registration Number: NCT00408356

Locations: 🇧🇩
ICDDR,B. Mirpur Field Site, Dhaka, Bangladesh

Improved Estimation of GFR by Cystatin C in Preventing Contrast Induced Nephropathy by NAC or Zn

Not Applicable

Terminated

Conditions: Chronic Kidney Failure

First Posted Date: 2006-11-14

Last Posted Date: 2007-02-01

Lead Sponsor: Robert Bosch Gesellschaft für Medizinische Forschung mbH

Target Recruit Count: 60

Registration Number: NCT00399256

Locations: 🇩🇪
Robert-Bosch-Hospital, Stuttgart, Germany

The CRISIS Prevention Study

Phase 3

Terminated

Conditions: Sepsis

Interventions: Other: saline
Drug: Metoclopramide
Other: sterile water
Drug: Zinc
Dietary Supplement: Glutamine
Other: selenium
Dietary Supplement: whey-protein

First Posted Date: 2006-11-02

Last Posted Date: 2013-04-18

Lead Sponsor: Michael Dean

Target Recruit Count: 293

Registration Number: NCT00395161

Locations: 🇺🇸
Childrens Hospital of Los Angeles, Los Angeles, California, United States
🇺🇸
University of California Los Angeles Medical Center, Los Angeles, California, United States
🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

and more 4 locations

Efficacy of Zinc Therapy in Acute Diarrhoea in Young Children

Phase 3

Completed

Conditions: Acute Watery Diarrhoea

First Posted Date: 2006-05-12

Last Posted Date: 2011-07-12

Lead Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh

Target Recruit Count: 2050

Registration Number: NCT00325247

Locations: 🇧🇩
ICDDR,B, Dhaka, Bangladesh

Impact of Zinc Supplementation in Low Birth Weight Infants on Severe Morbidity, Mortality and Zinc Status: A Randomized Controlled Trial

Not Applicable

Completed

Conditions: Diarrhea
Respiratory Infection
Low Birth Weight

First Posted Date: 2006-01-04

Last Posted Date: 2009-09-03

Lead Sponsor: Society for Applied Studies

Target Recruit Count: 2000

Registration Number: NCT00272142

Locations: 🇮🇳
Society for Applied Studies, New Delhi, Delhi, India

Zinc Supplementation in Cholera Patients

Phase 3

Completed

Conditions: Cholera

First Posted Date: 2005-09-27

Last Posted Date: 2005-10-20

Lead Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh

Registration Number: NCT00226616

Locations: 🇧🇩
ICDDR,B, Dhaka hospital, Dhaka, Bangladesh
🇧🇩
S.k.Roy, Dhaka, Bangladesh

A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer

Phase 2

Completed

Conditions: Squamous Cell Carcinoma of the Head and Neck

Interventions: Biological: IRX-2
Drug: Cyclophosphamide
Drug: Indomethacin
Drug: Zinc
Drug: Omeprazole

First Posted Date: 2005-09-21

Last Posted Date: 2020-12-11

Lead Sponsor: Brooklyn ImmunoTherapeutics, LLC

Target Recruit Count: 27

Registration Number: NCT00210470

Efficacy of Zinc in the Treatment of Pneumonia

Not Applicable

Completed

Conditions: Pneumonia

Interventions: Drug: Zinc

First Posted Date: 2005-09-20

Last Posted Date: 2015-01-12

Lead Sponsor: Johns Hopkins Bloomberg School of Public Health

Target Recruit Count: 299

Registration Number: NCT00198666

CHIZAP: Community- and Health Facility-Based Intervention With Zinc as Adjuvant Therapy for Childhood Pneumonia

Phase 2

Completed

Conditions: Pneumonia

Interventions: Drug: Zinc

First Posted Date: 2005-09-08

Last Posted Date: 2022-03-16

Lead Sponsor: Centre For International Health

Target Recruit Count: 2628

Registration Number: NCT00148733

Locations: 🇳🇵
Siddhi Memorial Hospital (SMH),Bhelukhel, Bhimsensthan, Bhaktapur, Nepal

Long-term Impact and Intervention for Diarrhea in Brazil

Phase 3

Conditions: Diarrheal Disorder

Interventions: Drug: Glutamine
Drug: Vitamin A
Drug: glycine
Drug: zinc

First Posted Date: 2005-08-23

Last Posted Date: 2011-03-08

Lead Sponsor: University of Virginia

Target Recruit Count: 321

Registration Number: NCT00133406

Locations: 🇧🇷
Federal University of Ceará, Fortaleza, Brazil

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