Talampanel

Generic Name
Talampanel
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C19H19N3O3
CAS Number
161832-65-1
Unique Ingredient Identifier
CVS43XG1L5
Background

Talampanel is a substance that is being studied in the treatment of brain tumors and other brain disorders, such as epilepsy and Parkinson disease. It is a type of AMPA receptor antagonist.

Indication

For the treatment of epilepsy.

Associated Conditions
-
Associated Therapies
-

Extension Study of Talampanel for Amyotrophic Lateral Sclerosis (ALS)

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2009-09-23
Last Posted Date
2013-08-26
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
446
Registration Number
NCT00982150

A Phase 1 Study to Investigate the Effects of Talampanel on the Heart Rhythm

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-08-25
Last Posted Date
2010-04-07
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
135
Registration Number
NCT00964730
Locations
🇺🇸

Cetero Research - Fargo, Fargo, North Dakota, United States

Talampanel for Amyotrophic Lateral Sclerosis (ALS)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-06-12
Last Posted Date
2011-10-21
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
559
Registration Number
NCT00696332
Locations
🇧🇪

Academic Hospital University of Leuven - ALS dept, Leuven, Belgium

🇫🇷

C.H.U. de Montpellier - Hopital Gui de Chauliac - Service des Explorations Neurologiques, Montpellier Cedex 5, France

🇨🇦

Montreal Neurological Institute, Montreal, Quebec, Canada

and more 21 locations

Talampanel to Treat Parkinson's Disease

Phase 2
Completed
Conditions
First Posted Date
2005-04-18
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Target Recruit Count
40
Registration Number
NCT00108667
Locations
🇺🇸

National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland, United States

Talampanel in Treating Patients With Recurrent High-Grade Glioma

Phase 2
Completed
Conditions
First Posted Date
2003-07-09
Last Posted Date
2012-03-08
Lead Sponsor
National Institutes of Health Clinical Center (CC)
Registration Number
NCT00064363
Locations
🇺🇸

Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support, Bethesda, Maryland, United States

Effect of Talampanel (an AMPA Receptor Blocker) on Brain Activity

Phase 2
Completed
Conditions
First Posted Date
2003-04-02
Last Posted Date
2008-03-04
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Target Recruit Count
25
Registration Number
NCT00057460
Locations
🇺🇸

National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland, United States

Effects of Talampanel on Patients With Advanced Parkinson's Disease

First Posted Date
2002-05-09
Last Posted Date
2011-04-13
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
22
Registration Number
NCT00036296

Multicenter Trial for Adults With Partial Seizures

Phase 2
Completed
Conditions
Interventions
First Posted Date
2002-05-03
Last Posted Date
2011-03-17
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
190
Registration Number
NCT00034814
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