Regramostim

Generic Name
Regramostim
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
127757-91-9
Unique Ingredient Identifier
KR89Q40F01
Background

Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and diff...

Indication

Investigated for use/treatment in adverse effects (chemotherapy) and bone marrow transplant.

Associated Conditions
-
Associated Therapies
-

A Personalized NeoAntigen Cancer Vaccine Combined With Anti-PD-1 in Melanoma

First Posted Date
2019-08-28
Last Posted Date
2020-04-28
Lead Sponsor
Xiangya Hospital of Central South University
Target Recruit Count
30
Registration Number
NCT04072900
Locations
🇨🇳

Xiangya Hospital, Central South University, Changsha, Hunan, China

Abscopal Effect of Radiation in Combination With rhGM-CSF for Metastatic Non-small Cell Lung Cancer

First Posted Date
2017-04-14
Last Posted Date
2023-06-13
Lead Sponsor
Peking University Cancer Hospital & Institute
Target Recruit Count
40
Registration Number
NCT03113851
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

A Study of SBRT in Combination With rhGM-CSF for Stage IV NSCLC Patients Who Failed in Second-line Chemotherapy

First Posted Date
2015-12-07
Last Posted Date
2018-10-15
Lead Sponsor
Wuhan University
Registration Number
NCT02623595
Locations
🇨🇳

Zhongnan hospital of Wuhan university, Wuhan, Hubei, China

RhGM-CSF as Adjuvant Immunotherapy in Treating Stage III Colon Cancer

Phase 2
Conditions
Interventions
First Posted Date
2015-06-09
Last Posted Date
2016-01-20
Lead Sponsor
The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
Target Recruit Count
60
Registration Number
NCT02466906
Locations
🇨🇳

307 Hospital of PLA, Beijing, Beijing, China

Study of Subcutaneous Injection of Low-dose rhGM-CSF +/- WLL in PAP.

First Posted Date
2013-11-14
Last Posted Date
2013-11-18
Lead Sponsor
Shanghai Pulmonary Hospital, Shanghai, China
Target Recruit Count
40
Registration Number
NCT01983657
Locations
🇨🇳

Shanghai Pulmonary Hospital, Shanghai, China

Recombinant Human Granulocyte Macrophage Colony Stimulating Factor(rhGM-CSF) Treating Oral Mucositis

First Posted Date
2013-03-07
Last Posted Date
2013-03-29
Lead Sponsor
Wei LUO
Target Recruit Count
160
Registration Number
NCT01806272
Locations
🇨🇳

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

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