Custirsen
- Generic Name
- Custirsen
- Brand Names
- -
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 890056-27-6
- Unique Ingredient Identifier
- L26E95NLRK
- Background
Custirsen is a benzopyran with potential antineoplastic activity. Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. Custirsen i...
- Indication
Investigated for use/treatment in brain cancer and breast cancer.
- Associated Conditions
- -
- Associated Therapies
- -
Thorough QT/QTc (Corrected QT Interval) Study to Evaluate the Effect of Custirsen on Cardiac Repolarization
- Conditions
- Interventions
- First Posted Date
- 2013-06-11
- Last Posted Date
- 2016-10-10
- Lead Sponsor
- Achieve Life Sciences
- Target Recruit Count
- 155
- Registration Number
- NCT01874561
- Locations
- ๐บ๐ธ
Teva Investigational Site 10565, Lenexa, Kansas, United States
A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer
- First Posted Date
- 2012-06-28
- Last Posted Date
- 2016-07-01
- Lead Sponsor
- Achieve Life Sciences
- Target Recruit Count
- 700
- Registration Number
- NCT01630733
- Locations
- ๐ช๐ธ
Hospital Universitario La Paz, Madrid, Spain
๐บ๐ธUniversity Cancer Institute, Soynton Beach, Florida, United States
๐ช๐ธHospital Universitario Doctor Peset, Valencia, Spain
Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With OGX-011 in Men With Prostate Cancer
- Conditions
- Interventions
- First Posted Date
- 2010-08-25
- Last Posted Date
- 2016-10-14
- Lead Sponsor
- Achieve Life Sciences
- Target Recruit Count
- 1022
- Registration Number
- NCT01188187
- Locations
- ๐ณ๐ฑ
Teva Investigational Site 852, Rotterdam, Netherlands
๐บ๐ธTeva Investigational Site 093, Marina del Rey, California, United States
๐บ๐ธTeva Investigational Site 100, Birmingham, Alabama, United States
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