Calcitonin gene-related peptide

Generic Name
Calcitonin gene-related peptide
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
83652-28-2
Unique Ingredient Identifier
JHB2QIZ69Z
Background

A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particul...

Indication

Investigated for use/treatment in myocardial infarction, heart disease, and asthma.

Associated Conditions
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Associated Therapies
-

Hypersensitivity to CGRP as a Predictive Biomarker of Migraine Prevention With Erenumab

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2020-10-19
Last Posted Date
2022-10-24
Lead Sponsor
Danish Headache Center
Target Recruit Count
400
Registration Number
NCT04592952
Locations
🇩🇰

Danish Headache Center, Copenhagen, Glostrup, Denmark

The Effect of Anti-calcitonin Gene-related Peptide (CGRP) Receptor Antibodies on the Headache Inducing Properties of CGRP and Cilostazol in Migraine Patients

First Posted Date
2020-07-01
Last Posted Date
2020-10-08
Lead Sponsor
Danish Headache Center
Target Recruit Count
72
Registration Number
NCT04452929
Locations
🇩🇰

Danish Headache Center, Glostrup, Denmark

Clinical Characteristics and Pathophysiology of Post-Traumatic Headache

First Posted Date
2019-01-02
Last Posted Date
2020-01-29
Lead Sponsor
Danish Headache Center
Target Recruit Count
200
Registration Number
NCT03791515
Locations
🇩🇰

Danish Headache Center, Glostrup, Denmark

The Effect of Sumatriptan and Placebo on CGRP Induced Headache

First Posted Date
2018-05-31
Last Posted Date
2019-09-12
Lead Sponsor
Danish Headache Center
Target Recruit Count
30
Registration Number
NCT03542357
Locations
🇩🇰

Rigshospitalet Glostrup, Glostrup, Denmark

CGRP-induced Migraine Attacks in Patients Who Have Tried Anti-CGRP Monoclonal Antibody Treatment

First Posted Date
2018-03-29
Last Posted Date
2018-03-29
Lead Sponsor
Danish Headache Center
Target Recruit Count
40
Registration Number
NCT03481400
Locations
🇩🇰

Danish Headache Center, Rigshospitalet Glostrup, Copenhagen, Glostrup, Denmark

Pharmacologically Triggered Migraine Without Aura and Neuroimaging

First Posted Date
2017-05-08
Last Posted Date
2019-02-15
Lead Sponsor
Danish Headache Center
Target Recruit Count
36
Registration Number
NCT03143465
Locations
🇩🇰

Danish Headache Center, University Hospital, Glostrup, Denmark

CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2013-08-16
Last Posted Date
2022-08-02
Lead Sponsor
Danish Headache Center
Target Recruit Count
40
Registration Number
NCT01924052

Calcitonin Gene-related Peptide in Familial Hemiplegic Migraine (FHM) and Migraine With Aura (MA)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2008-06-02
Last Posted Date
2009-08-03
Lead Sponsor
Danish Headache Center
Target Recruit Count
30
Registration Number
NCT00687947
Locations
🇩🇰

Danish Headache Center, University of Copenhagen, Faculty of Health Sciences, Department of Neurology, Glostrup Hospital, Glostrup, Copenhagen, Denmark

Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.

Not Applicable
Completed
Conditions
First Posted Date
2006-08-01
Last Posted Date
2006-11-10
Lead Sponsor
Danish Headache Center
Target Recruit Count
20
Registration Number
NCT00358839
Locations
🇩🇰

Danish Headache Center, Glostrup, Copenhagen, Denmark

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