Erenumab

Generic Name
Erenumab
Brand Names
Aimovig
Drug Type
Biotech
Chemical Formula
-
CAS Number
1582205-90-0
Unique Ingredient Identifier
I5I8VB78VT
Background

Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only FDA approved treatment specificall...

Indication

Erenumab is indicated for the preventative treatment of migraine in adults .

Associated Conditions
Migraine
Associated Therapies
-

Investigational Use of Erenumab for the Treatment of Fibromyalgia Pain

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2024-05-13
Last Posted Date
2024-05-13
Lead Sponsor
United States Naval Medical Center, Portsmouth
Target Recruit Count
5
Registration Number
NCT06411067
Locations
🇺🇸

Naval Medical Center Portsmouth, Portsmouth, Virginia, United States

Aimovig Pregnancy Exposure Registry

Recruiting
Conditions
Interventions
First Posted Date
2023-11-29
Last Posted Date
2024-10-03
Lead Sponsor
Amgen
Target Recruit Count
2842
Registration Number
NCT06150781
Locations
🇺🇸

IQVIA Virtual Site, Durham, North Carolina, United States

Screening Trial for Pain Relief in Schwannomatosis (STARFISH)

First Posted Date
2023-01-13
Last Posted Date
2024-03-13
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
40
Registration Number
NCT05684692
Locations
🇺🇸

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Real World Effectiveness of Eptinezumab in Participants With Migraine

First Posted Date
2022-03-17
Last Posted Date
2024-05-29
Lead Sponsor
H. Lundbeck A/S
Target Recruit Count
32
Registration Number
NCT05284019
Locations
🇺🇸

Gilbert Neurology Partners/ CCT Research, Gilbert, Arizona, United States

🇺🇸

Ki Clinical Research LLC, dba New England Institute for Clinical Research, Stamford, Connecticut, United States

🇺🇸

Innovation Medical Group, Palmetto Bay, Florida, United States

and more 7 locations

Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study

First Posted Date
2022-03-16
Last Posted Date
2022-10-20
Lead Sponsor
Austrian Migraine Registry Collaboration
Target Recruit Count
1500
Registration Number
NCT05281770
Locations
🇦🇹

Medical University Innsbruck, Innsbruck, Tirol, Austria

🇦🇹

Clinic Hietzing, Vienna, Austria

🇦🇹

Medizinische Universität Wien, Wien, Vienna, Austria

Erenumab-aooe for the Management of Trigeminal Neuropathic Pain.

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2021-12-02
Last Posted Date
2024-03-22
Lead Sponsor
University of Maryland, Baltimore
Target Recruit Count
5
Registration Number
NCT05142228
Locations
🇺🇸

University of Maryland, School of Dentistry, Brotman Facial Pain Clinic, Baltimore, Maryland, United States

Management of Migraine Using Enerumab and Traditional Therapy at the Time of COVID-19

Completed
Conditions
First Posted Date
2021-09-21
Last Posted Date
2021-09-21
Lead Sponsor
Fayoum University
Target Recruit Count
90
Registration Number
NCT05052008
Locations
🇪🇬

Marwa Kamal Ahmed Tolba, Fayoum, Egypt

A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Migraine

Phase 4
Completed
Conditions
Interventions
First Posted Date
2021-04-01
Last Posted Date
2023-10-06
Lead Sponsor
Amgen
Target Recruit Count
240
Registration Number
NCT04825678
Locations
🇺🇸

Asheville Neurology Specialists PA, Asheville, North Carolina, United States

🇺🇸

New Age Medical Research Corporation, Miami, Florida, United States

🇺🇸

Mountain Neurological Research Center, Basalt, Colorado, United States

and more 39 locations

Registry for Migraine - Structural and Functional MRI Before and After Erenumab Treatment

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2020-12-17
Last Posted Date
2022-01-10
Lead Sponsor
Danish Headache Center
Target Recruit Count
250
Registration Number
NCT04674020
Locations
🇩🇰

Danish Headache Center, Copenhagen, Denmark

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