Clazosentan

Generic Name
Clazosentan
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C25H23N9O6S
CAS Number
180384-56-9
Unique Ingredient Identifier
3DRR0X4728
Indication

Investigated for use/treatment in strokes.

Associated Conditions
-
Associated Therapies
-

A Study in Healthy Subjects to Investigate Whether Administration of Clazosentan Can Affect Normal Heart Function

First Posted Date
2018-09-05
Last Posted Date
2018-11-20
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
36
Registration Number
NCT03657446
Locations
🇳🇱

QPS Netherlands B.V., Groningen, Netherlands

A Study in Healthy Male Subjects to Investigate Whether Administration of Rifampicin Can Affect the Fate of Clazosentan in the Body of Clazosentan

First Posted Date
2018-07-23
Last Posted Date
2018-10-23
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
14
Registration Number
NCT03596294
Locations
🇳🇱

QPS Netherlands B.V., Groningen, Netherlands

Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the Brain

First Posted Date
2018-07-12
Last Posted Date
2024-01-10
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
409
Registration Number
NCT03585270
Locations
🇺🇸

University of Illinois - Department of Neurosurgery, Chicago, Illinois, United States

🇺🇸

University Hospitals Case Medical Center - Department of Neurosurgery, Cleveland, Ohio, United States

🇭🇺

Debreceni Egyetem, Idegsebészet, Debrecen, Hungary

and more 77 locations

Evaluation of the Efficacy and Safety of Clazosentan in Reversing Cerebral Vasospasm in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage

Phase 2
Completed
Conditions
Interventions
First Posted Date
2015-09-25
Last Posted Date
2018-07-10
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
25
Registration Number
NCT02560532
Locations
🇫🇷

Site 1002, Bron, France

🇫🇷

Site 1004, Marseille, France

🇨🇭

Site 3001, Basel, Switzerland

and more 8 locations

Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Surgical Clipping

First Posted Date
2007-11-14
Last Posted Date
2020-02-17
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
1157
Registration Number
NCT00558311
Locations
🇩🇪

Thechnical University-Klinikum rechts der Isar, Munich, Germany

🇺🇸

State University of New York at Stony Brook-Health Sciences Center, Stony Brook, New York, United States

🇺🇸

University of Cincinnati-Department of Neurosurgery, Cincinnati, Ohio, United States

and more 113 locations
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