Fospropofol
- Generic Name
- Fospropofol
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C13H21O5P
- CAS Number
- 258516-89-1
- Unique Ingredient Identifier
- LZ257RZP7K
- Background
Fospropofol is a water soluble prodrug and is converted to propofol in the liver. Fospropofol is a short acting hypnotic/sedative/anesthetic agent. Unlike propofol, does not cause injection-site pain as it is unable to activate TRPA1. FDA approved in December 2008.
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- Indication
For monitored anaesthesia care sedation in patients undergoing diagnostic procedures like bronchoscopy and colonscopy or minor surgical procedures like arthroscopy and bunionectomy.
- Associated Conditions
- -
- Associated Therapies
- Monitored anesthesia care sedation
Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial
- First Posted Date
- 2024-08-27
- Last Posted Date
- 2024-08-27
- Lead Sponsor
- Hui Xu
- Target Recruit Count
- 373
- Registration Number
- NCT06573489
ED90 of Fospropofol Disodium in Induction and Maintenance of Anesthesia
- First Posted Date
- 2024-04-03
- Last Posted Date
- 2024-07-03
- Lead Sponsor
- Tongji Hospital
- Target Recruit Count
- 330
- Registration Number
- NCT06344325
- Locations
- 🇨🇳
Tongji hospital, Wuhan, Hubei, China
Safety and Efficacy of Fospropofol vs Propofol During Invasive Mechanical Ventilation.
Not Applicable
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-02-15
- Last Posted Date
- 2024-02-15
- Lead Sponsor
- Henan Provincial People's Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT06261996
Preventing Propofol Injection Pain: Prospective Randomized Trial Comparing Propofol Versus Fospropofol
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2011-07-25
- Last Posted Date
- 2017-12-29
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 116
- Registration Number
- NCT01401049
- Locations
- 🇺🇸
NYU Langone Medical Center, New York, New York, United States
Fospropofol for Sedation During Elective Awake Intubation
- First Posted Date
- 2011-02-03
- Last Posted Date
- 2017-04-18
- Lead Sponsor
- The Cleveland Clinic
- Registration Number
- NCT01289483
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
Comparison of AQUAVAN® Injection to DISOPRIVAN® Injectable Emulsion for Anesthesia During Coronary Artery Surgery
Phase 2
Completed
- Conditions
- Interventions
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2010-06-11
- Lead Sponsor
- Eisai Inc.
- Target Recruit Count
- 16
- Registration Number
- NCT00209521
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