Buserelin

Generic Name
Buserelin
Brand Names
Suprefact
Drug Type
Small Molecule
Chemical Formula
C60H86N16O13
CAS Number
57982-77-1
Unique Ingredient Identifier
PXW8U3YXDV
Background

Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR). It is used in prostate cancer treatment.

Indication

Buserelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction.

Associated Conditions
Endometriosis, Stage D2 Prostatic carcinoma
Associated Therapies
-

Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score

First Posted Date
2021-09-20
Last Posted Date
2024-11-27
Lead Sponsor
NRG Oncology
Target Recruit Count
2050
Registration Number
NCT05050084
Locations
🇺🇸

Arizona Center for Cancer Care - Gilbert, Gilbert, Arizona, United States

🇺🇸

Arizona Center for Cancer Care-Peoria, Peoria, Arizona, United States

🇺🇸

Arizona Center for Cancer Care - Phoenix, Phoenix, Arizona, United States

and more 532 locations

Age Versus Ovarian Reserve Markers Based Therapy in IVF (IVF)/Intracytoplasmic Sperm Injection (ICSI) Cycles

First Posted Date
2013-03-22
Last Posted Date
2016-12-23
Lead Sponsor
Andros Day Surgery Clinic
Target Recruit Count
194
Registration Number
NCT01816789
Locations
🇮🇹

ANDROS Day Surgery Clinic, Palermo, Sicily, Italy

Mild Stimulation Protocol Versus Microdose Gonadotropin-releasing Hormone Agonist Flare up Protocol in Poor Responders

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-10-01
Last Posted Date
2010-10-01
Lead Sponsor
Yazd Medical University
Target Recruit Count
159
Registration Number
NCT01213147
Locations
🇮🇷

Yazd Research and Clinical Center for Infertility, Yazd, Iran, Islamic Republic of

Clomiphene Citrate (CC)/Gonadotropin/Gonadotropin Releasing Hormone (GnRH) Antagonist Versus Gonadotropin/GnRH Agonist

First Posted Date
2009-01-28
Last Posted Date
2009-01-28
Lead Sponsor
Yazd Research & Clinical Center for Infertility
Target Recruit Count
200
Registration Number
NCT00830492
Locations
🇮🇷

Yazd Research and Clinical Center For Infertility, Yazd, Iran, Islamic Republic of

Agonist Gonadotropin-Releasing Hormone (GnRH) Versus Antagonist GnRH

Phase 3
Conditions
Interventions
First Posted Date
2009-01-15
Last Posted Date
2009-01-15
Lead Sponsor
Yazd Research & Clinical Center for Infertility
Target Recruit Count
2
Registration Number
NCT00823602
Locations
🇮🇷

Yazd Research and Clinical Center For Infertility, Yazd, Iran, Islamic Republic of

Replacement of Fresh Embryo Transfers (ETs) by Frozen Embryo Transfers (FETs) Using Vitrification

First Posted Date
2009-01-15
Last Posted Date
2010-01-20
Lead Sponsor
Yazd Research & Clinical Center for Infertility
Target Recruit Count
500
Registration Number
NCT00823121
Locations
🇮🇷

: Research and clinical center for infertility, Yazd, Iran, Islamic Republic of

Androgen Suppression and Radiation With/Out Docetaxel in High-Risk Localized Prostate Cancer

First Posted Date
2008-04-02
Last Posted Date
2023-08-04
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
48
Registration Number
NCT00651326
Locations
🇨🇦

McGill University - Dept. Oncology, Montreal, Canada

🇨🇦

Tom Baker Cancer Centre, Calgary, Canada

🇨🇦

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Canada

and more 10 locations

Hormone Therapy and OGX-011 Before Radical Prostatectomy in Treating Patients With Prostate Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-02-06
Last Posted Date
2023-08-04
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
25
Registration Number
NCT00054106
Locations
🇨🇦

British Columbia Cancer Agency - Vancouver Cancer Centre, Vancouver, British Columbia, Canada

Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2020-04-03
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
361
Registration Number
NCT00002633
Locations
🇨🇦

QEII Health Sciences Center, Halifax, Nova Scotia, Canada

🇨🇦

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario, Canada

🇨🇦

Cancer Centre of Southeastern Ontario at Kingston, Kingston, Ontario, Canada

and more 12 locations
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