Levomilnacipran

Generic Name
Levomilnacipran
Brand Names
Fetzima
Drug Type
Small Molecule
Chemical Formula
C15H22N2O
CAS Number
96847-54-0
Unique Ingredient Identifier
UGM0326TXX
Background

Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake. Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran. Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in hum...

Indication

Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor indicated for the treatment of major depressive disorder (MDD) in adults.

Associated Conditions
Major Depressive Disorder (MDD)
Associated Therapies
-

Levomilnacipran in Healthy Males

First Posted Date
2017-08-15
Last Posted Date
2021-10-06
Lead Sponsor
University of Ottawa
Target Recruit Count
36
Registration Number
NCT03249311
Locations
🇨🇦

Institute of Mental Health Research, Royal Ottawa Mental Health Centre, Ottawa, Ontario, Canada

Levomilnacipran ER vs. Adjunctive Quetiapine for Adults With Inadequate Relief With SSRIs in MDD

First Posted Date
2016-03-25
Last Posted Date
2019-08-14
Lead Sponsor
Duke University
Target Recruit Count
60
Registration Number
NCT02720198
Locations
🇺🇸

Institute for Advanced Medical Research, Alpharetta, Georgia, United States

Trial of Levomilnacipran in Geriatric Depression

First Posted Date
2015-06-09
Last Posted Date
2019-08-14
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
29
Registration Number
NCT02466958
Locations
🇺🇸

UCLA Semel Institute - Neuropsychiatric Institute (NPI), Los Angeles, California, United States

Safety and Efficacy of Levomilnacipran ER in Adolescent Participants With Major Depressive Disorder

First Posted Date
2015-05-01
Last Posted Date
2020-09-07
Lead Sponsor
Forest Laboratories
Target Recruit Count
552
Registration Number
NCT02431806
Locations
🇺🇸

Innovative Clinical Research, Inc., Lauderhill, Florida, United States

🇺🇸

Professional Psychiatric Services, Mason, Ohio, United States

🇺🇸

Carilion Medical Center, Roanoke, Virginia, United States

and more 45 locations

Novel Medication as a Potential Smoking Cessation Aid

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2014-10-15
Last Posted Date
2022-04-22
Lead Sponsor
University of Minnesota
Target Recruit Count
56
Registration Number
NCT02265367
Locations
🇺🇸

Clinical and Translational Sciences Institute, Minneapolis, Minnesota, United States

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