Galidesivir

Generic Name
Galidesivir
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C11H15N5O3
CAS Number
249503-25-1
Unique Ingredient Identifier
OLF97F86A7
Background

Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus. In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various pathogens, including Ebola, Marburg, Yellow Fever and Zika viruses. In vitro, it displayed broad-spectrum antiviral activity against various negative-...

Associated Conditions
-
Associated Therapies
-

A Study to Evaluate the Safety, Pharmacokinetics and Antiviral Effects of Galidesivir in Yellow Fever or COVID-19

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2019-03-27
Last Posted Date
2021-05-27
Lead Sponsor
BioCryst Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT03891420
Locations
🇧🇷

Hospital de Clinicas da Universidade Federal do Parana, Curitiba, Parana, Brazil

🇧🇷

Foundation Regional Faculty of Medicine of São José do Rio Preto, São José Do Rio Preto, SP, Brazil

🇧🇷

Clinical Research Unit and Department of Infectious and Parasitic Diseases Hospital das Clínicas, School of Medicine, USP, São Paulo, SP, Brazil

and more 2 locations

A Study to Evaluate the Single Dose Safety, Tolerability and Pharmacokinetics of IV BCX4430

Phase 1
Completed
Conditions
Interventions
First Posted Date
2019-01-11
Last Posted Date
2021-07-23
Lead Sponsor
BioCryst Pharmaceuticals
Target Recruit Count
32
Registration Number
NCT03800173
Locations
🇺🇸

PRA Health Sciences, Lenexa, Kansas, United States

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