Lebrikizumab

Generic Name
Lebrikizumab
Brand Names
Ebglyss
Drug Type
Biotech
Chemical Formula
-
CAS Number
953400-68-5
Unique Ingredient Identifier
U9JLP7V031
Background

Lebrikizumab has been used in trials studying the treatment of Asthma, Allergic Asthma, Atopic Dermatitis, Idiopathic Pulmonary Fibrosis, and COPD, Chronic Obstructive Pulmonary Disease.

Associated Conditions
-
Associated Therapies
-

A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic Dermatitis

First Posted Date
2024-02-28
Last Posted Date
2024-12-09
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
430
Registration Number
NCT06280716
Locations
🇰🇷

Korea University Ansan Hospital, Ansan-si, KyÇ’nggi-do, Korea, Republic of

🇰🇷

National Medical Center, Seoul, Seoul-teukbyeolsi [Seoul], Korea, Republic of

🇰🇷

Asan Medical Center, Seoul, Seoul-teukbyeolsi [Seoul], Korea, Republic of

and more 44 locations

A Study to Investigate the Safety and Pharmacokinetics of Lebrikizumab in Healthy Chinese Participants

Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2024-02-06
Last Posted Date
2024-06-25
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
24
Registration Number
NCT06243198
Locations
🇨🇳

Peking University People's Hospital, Beijing, Beijing, China

A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

First Posted Date
2023-02-21
Last Posted Date
2024-08-29
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
250
Registration Number
NCT05735483
Locations
🇺🇸

First OC Dermatology, Fountain Valley, California, United States

🇺🇸

Dermatology Research Associates, Los Angeles, California, United States

🇨🇦

DermEdge Research, Mississauga, Ontario, Canada

and more 91 locations

A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

First Posted Date
2022-09-29
Last Posted Date
2024-12-13
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
360
Registration Number
NCT05559359
Locations
🇺🇸

Great Lakes Research Group, Inc., Bay City, Michigan, United States

🇯🇵

Asahikawa Medical College Hospital, Asahikawa, Hokkaido, Japan

🇺🇸

Antelope Valley Clinical Trials, Lancaster, California, United States

and more 96 locations

A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2022-05-12
Last Posted Date
2024-12-09
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
80
Registration Number
NCT05372419
Locations
🇺🇸

Dermatology Research Associates, Los Angeles, California, United States

🇺🇸

Wallace Medical Group, Inc., Los Angeles, California, United States

🇺🇸

Clinical Science Institute, Santa Monica, California, United States

and more 32 locations

A Study of Lebrikizumab (LY3650150) in Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis Previously Treated With Dupilumab

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2022-05-11
Last Posted Date
2024-11-27
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
120
Registration Number
NCT05369403
Locations
🇺🇸

Direct Helpers Research Center, Hialeah, Florida, United States

🇺🇸

Skin Care Physicians of Georgia, Macon, Georgia, United States

🇺🇸

Miami Dermatology and Laser Research, Miami, Florida, United States

and more 34 locations

A Study of Lebrikizumab in Combination With Topical Corticosteroids in Patients With Atopic Dermatitis (AD) That Are Not Adequately Controlled With or Are Non-eligible for Cyclosporine

First Posted Date
2021-12-08
Last Posted Date
2024-11-06
Lead Sponsor
Almirall, S.A.
Target Recruit Count
331
Registration Number
NCT05149313
Locations
🇫🇷

Alm Site 12, Reims, France

🇳🇱

Alm Site 35, Utrecht, Netherlands

🇫🇷

Alm Site 19, Lille, France

and more 45 locations

A Study of Lebrikizumab (LY3650150) Administered by Two Different Devices in Healthy Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2021-04-12
Last Posted Date
2024-11-22
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
242
Registration Number
NCT04840901
Locations
🇺🇸

QPS, Springfield, Missouri, United States

🇺🇸

LabCorp CRU, Inc., Madison, Wisconsin, United States

🇺🇸

Covance Dallas, Dallas, Texas, United States

A Study of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroids in Japanese Participants With Moderate-to-Severe Atopic Dermatitis

First Posted Date
2021-02-18
Last Posted Date
2023-08-23
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
286
Registration Number
NCT04760314
Locations
🇯🇵

Hiroshima University Hospital, Hiroshima-shi, Hiroshima-ken, Japan

🇯🇵

KAJI Dermatology Clinic, Nonoichi-shi, Ishikawa, Japan

🇯🇵

Kosugi Dermatology Clinic, Kawasaki, Kanagawa, Japan

and more 34 locations

A Study of Lebrikizumab (LY3650150) on Vaccine Response in Adults With Atopic Dermatitis (ADopt-VA)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2020-11-12
Last Posted Date
2023-10-17
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
254
Registration Number
NCT04626297
Locations
🇺🇸

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

🇺🇸

Modern Research Associates, Dallas, Texas, United States

🇺🇸

Premier Clinical Research, Spokane, Washington, United States

and more 81 locations
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